The new incretin-based therapies, dipeptidyl peptidase-4 (DPP4) inhibitors and glucagon
like peptide 1 (GLP1) receptor agonists are widely used for the treatment of type 2 diabetes …

microRNAs are small RNAs that regulate protein synthesis post-transcriptionally. Animal
microRNAs recognize their targets by incomplete base pairing to sequence motifs most often …

Drug resistance in parasitic nematodes is an increasing problem worldwide, with resistance
reported to all three commonly used classes of anthelmintics. Most studies to date have …

MicroRNAs (miRNAs) bind to Argonaute proteins, and together they form the RISC complex
and regulate target mRNA translation and/or stability. Identification of mRNA targets is key to …

MicroRNAs (miRNAs) are small regulatory RNA molecules functioning to modulate gene
expression at the post-transcriptional level, and playing an important role in many …

A strong, negative cis-element located at the first intron+ 502/+ 835 (I300) of zebrafish myf 5
has been reported. To elucidate the molecular mechanism underlying this repression …

We review the pertinent literature on methods used in high-throughput experimental
identification of microRNA (miRNA)“targets” with emphasis on neurochemical studies …

To study the function of a miRNA, it is necessary to identify its target genes. The most
common methods to reveal miRNA target genes rely on ectopically expressed tagged Ago2 …