Acute administration of cannabidiol in vivo suppresses ischaemia‐induced cardiac arrhythmias and reduces infarct size when given at reperfusion
SK Walsh, CY Hepburn, KA Kane… - British journal of …, 2010 - Wiley Online Library
Background and purpose: Cannabidiol (CBD) is a phytocannabinoid, with anti‐apoptotic,
anti‐inflammatory and antioxidant effects and has recently been shown to exert a tissue …
anti‐inflammatory and antioxidant effects and has recently been shown to exert a tissue …
Aldehyde dehydrogenase activation prevents reperfusion arrhythmias by inhibiting local renin release from cardiac mast cells
K Koda, M Salazar-Rodriguez, F Corti, NYK Chan… - Circulation, 2010 - Am Heart Assoc
Background—Renin released by ischemia/reperfusion from cardiac mast cells activates a
local renin-angiotensin system (RAS). This exacerbates norepinephrine release and …
local renin-angiotensin system (RAS). This exacerbates norepinephrine release and …
Acute cardioprotective and cardiotoxic effects of bilberry anthocyanins in ischemia–reperfusion injury: beyond concentration-dependent antioxidant activity
L Ziberna, M Lunder, S Moze, A Vanzo, F Tramer… - Cardiovascular …, 2010 - Springer
Despite being reported to reduce the risk of cardiovascular diseases, little is known about
acute direct effects of bilberry anthocyanins on whole mammalian heart under ischemia …
acute direct effects of bilberry anthocyanins on whole mammalian heart under ischemia …
Role of mitochondrial dysfunction in cardiac glycoside toxicity
T Liu, DA Brown, B O'Rourke - Journal of molecular and cellular cardiology, 2010 - Elsevier
Cardiac glycosides, which inhibit the plasma membrane Na+ pump, are one of the four
categories of drug recommended for routine use to treat heart failure, yet their therapeutic …
categories of drug recommended for routine use to treat heart failure, yet their therapeutic …
Antiarrhythmic effects and ionic mechanisms of oxymatrine from Sophora flavescens
C Yong‐gang, J Shan, L Lei, G Jing‐quan… - Phytotherapy …, 2010 - Wiley Online Library
Accumulating evidence indicates that oxymatrine may exert protective effects on the
cardiovascular system. This study was designed to evaluate the antiarrhythmic effects as …
cardiovascular system. This study was designed to evaluate the antiarrhythmic effects as …
Both mitochondrial KATP channel opening and sarcolemmal KATP channel blockage confer protection against ischemia/reperfusion-induced arrhythmia in …
E Gonca, Ö Bozdoğan - Journal of cardiovascular …, 2010 - journals.sagepub.com
Aim: This study was performed to assess the effect of selective sarcolemmal adenosine
triphosphate (ATP)-sensitive K+ channel (KATP) inhibition and the mitochondrial KATP …
triphosphate (ATP)-sensitive K+ channel (KATP) inhibition and the mitochondrial KATP …
Mitochondrial KATP channel inhibition blunts arrhythmia protection in ischemic exercised hearts
JC Quindry, L Schreiber, P Hosick… - American Journal …, 2010 - journals.physiology.org
The mechanisms responsible for anti-arrhythmic protection during ischemia-reperfusion (IR)
in exercised hearts are not fully understood. The purpose of this investigation was to …
in exercised hearts are not fully understood. The purpose of this investigation was to …
Antiarrhythmic, serotonin antagonist and antianxiety activities of novel substituted thiophene derivatives synthesized from 2-amino-4, 5, 6, 7-tetrahydro-N-phenylbenzo …
A series of novel thiophene derivatives 3–17 were synthesized by initial reactions of 2-
amino-4, 5, 6, 7-tetrahydro-N-phenylbenzo [b] thiophene-3-carboxamide 1 and 2-amino-4, 5 …
amino-4, 5, 6, 7-tetrahydro-N-phenylbenzo [b] thiophene-3-carboxamide 1 and 2-amino-4, 5 …
Insulin and resveratrol act synergistically, preventing cardiac dysfunction in diabetes, but the advantage of resveratrol in diabetics with acute heart attack is …
JP Huang, SS Huang, JY Deng, CC Chang… - Free Radical Biology …, 2010 - Elsevier
Resveratrol (RSV), a natural phenolic compound, has been found to display cardiovascular
protective and insulin-sensitizing properties. In this study, the effects of RSV and its …
protective and insulin-sensitizing properties. In this study, the effects of RSV and its …
Oxytocin protects rat heart against ischemia–reperfusion injury via pathway involving mitochondrial ATP-dependent potassium channel
AM Alizadeh, M Faghihi, HR Sadeghipour… - Peptides, 2010 - Elsevier
Cardiac preconditioning represents the most potent and consistently reproducible method of
rescuing heart tissue from undergoing irreversible ischemic damage. One of the major goals …
rescuing heart tissue from undergoing irreversible ischemic damage. One of the major goals …