This document details the procedures and recommendations of the Goals and Metrics
Committee of the Strategic Planning Task Force of the American Heart Association, which …

The recommendations listed in this document are, whenever possible, evidence based. An
extensive evidence review was conducted for the period beginning March 2008 through …

This review focuses on mechanisms and emerging concepts that drive the science of stroke
in a therapeutic direction. Once considered exclusively a disorder of blood vessels, growing …

In the United States, the incidence rate of new or recurrent stroke is approximately 795 000
per year, and stroke prevalence for individuals over the age of 20 years is estimated at 6.5 …

Cardiac hypertrophy can be defined as an increase in heart mass. Pathological cardiac
hypertrophy (heart growth that occurs in settings of disease, eg hypertension) is a key risk …

Approximately 79 400 000 American adults, or 1 in 3, have cardiovascular disease (CVD). 1
CVD accounts for 36.3% or 1 of every 2.8 deaths in the United States and is the leading …

Loneliness is a prevalent social problem with serious physiological and health implications.
However, much of the research to date is based on cross-sectional data, including our own …

Cardiovascular disease is a major complication of diabetes mellitus, and improved
strategies for prevention and treatment are needed. Endothelial dysfunction contributes to …

Since the initial description of the phenomenon by Jennings et al 50 years ago, our
understanding of the underlying mechanisms of reperfusion injury has grown significantly …

Cigarette smoking is a well-established risk factor for all forms of stroke. While both the
general public and the global healthcare system are aware of the vascular risks associated …