Oxidative stress and aging: is methylglyoxal the hidden enemy?

KM Desai, T Chang, H Wang… - Canadian journal of …, 2010 - cdnsciencepub.com
Aging is a multifactorial process that involves changes at the cellular, tissue, organ and the
whole body levels resulting in decreased functioning, development of diseases, and …

Methylglyoxal induces cellular damage by increasing argpyrimidine accumulation and oxidative DNA damage in human lens epithelial cells

J Kim, NH Kim, E Sohn, CS Kim, JS Kim - Biochemical and biophysical …, 2010 - Elsevier
Methylglyoxal (MGO) is a cytotoxic metabolite and modifies tissue proteins through the
Maillard reaction, resulting in advanced glycation end products (AGEs), which can alter …

Cytotoxic role of methylglyoxal in rat retinal pericytes: Involvement of a nuclear factor-kappaB and inducible nitric oxide synthase pathway

J Kim, OS Kim, CS Kim, NH Kim, JS Kim - Chemico-biological interactions, 2010 - Elsevier
Methylglyoxal (MGO), a cytotoxic metabolite, is produced from glycolysis. Elevated levels of
MGO are observed in a number of diabetic complications, including retinopathy …

乙二醛酶Ⅰ 与糖尿病并发症的关系

李智, 闫世军, 王思彤, 盛军, 张文生 - 中国药理学通报, 2010 - cqvip.com
乙二醛酶Ⅰ与糖尿病并发症的关系-[维普官方网站]-www.cqvip.com-维普网  我的维普 购物车
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Methylglyoxal, oxidative stress, and aging

MP Kalapos, KM Desai, L Wu - Aging and Age-Related Disorders, 2010 - Springer
Methylglyoxal (MG) is a highly reactive product of mainly glucose metabolism. Reactive
oxygen species (ROS) are produced during various biochemical reactions, including …