TOR-dependent control of autophagy: biting the hand that feeds
TP Neufeld - Current opinion in cell biology, 2010 - Elsevier
Induction of autophagy in response to starvation is a highly conserved ability of eukaryotic
cells, indicating a crucial and ancient role of this process in adapting to nutrient conditions …
cells, indicating a crucial and ancient role of this process in adapting to nutrient conditions …
mTOR signaling in lymphangioleiomyomatosis
AS Kristof - Lymphatic research and biology, 2010 - liebertpub.com
The protein mammalian target of rapamycin (mTOR) plays a central role in cell growth and
proliferation. Excessive mTOR activity is a prominent feature of many neoplasms and …
proliferation. Excessive mTOR activity is a prominent feature of many neoplasms and …
Autophagy facilitates IFN-γ-induced Jak2-STAT1 activation and cellular inflammation
YP Chang, CC Tsai, WC Huang, CY Wang… - Journal of Biological …, 2010 - ASBMB
Autophagy is regulated for IFN-γ-mediated antimicrobial efficacy; however, its molecular
effects for IFN-γ signaling are largely unknown. Here, we show that autophagy facilitates IFN …
effects for IFN-γ signaling are largely unknown. Here, we show that autophagy facilitates IFN …
The regulation of STAT1 nuclear content by Mammalian Target of Rapamycin
J Tan - 2010 - escholarship.mcgill.ca
Mammalian target of rapamycin (mTOR) is a highly conserved serine/threonine kinase that
controls cell growth. In yeast, in addition to its regulation of cell growth, TOR lowers the …
controls cell growth. In yeast, in addition to its regulation of cell growth, TOR lowers the …