Endothelial dysfunction, inflammation, and apoptosis in diabetes mellitus

IAM van den Oever, HG Raterman… - Mediators of …, 2010 - Wiley Online Library
Endothelial dysfunction is regarded as an important factor in the pathogenesis of vascular
disease in obesity‐related type 2 diabetes. The imbalance in repair and injury …

Treatment for radiation-induced pulmonary late effects: spoiled for choice or looking in the wrong direction?

JP Williams, CJ Johnston… - Current drug targets, 2010 - ingentaconnect.com
Due to the radiosensitivity of the lung, toxic endpoints, in the form of radiation pneumonitis
and pulmonary fibrosis, are relatively frequent outcomes following radiation treatment of …

Crucial role of renin-angiotensin system in the pathogenesis of atherosclerosis

M Sata, D Fukuda - The Journal of Medical Investigation, 2010 - jstage.jst.go.jp
The renin-angiotensin system (RAS) has been demonstrated to play a critical role in the
initiation and progression of atherosclerosis, thereby contributing to development of …

Renin-angiotensin system activation correlates with microvascular dysfunction in a prospective cohort study of clinical sepsis

KC Doerschug, AS Delsing, GA Schmidt, A Ashare - Critical Care, 2010 - Springer
Introduction Microvascular dysregulation characterized by hyporesponsive vessels and
heterogeneous bloodflow is implicated in the pathogenesis of organ failure in sepsis. The …

Modulation of the renin–angiotensin–aldosterone system in sepsis: a new therapeutic approach?

DR Salgado, JR Rocco, E Silva… - Expert opinion on …, 2010 - Taylor & Francis
Importance of the field: Severe sepsis is characterized by relative hypotension associated
with a high cardiac output, peripheral vasodilation, and organ dysfunction. The renin …

Biomarkers of inflammation and endothelial dysfunction and risk of hypertension among Inner Mongolians in China

Y Zhang, AM Thompson, W Tong, T Xu… - Journal of …, 2010 - journals.lww.com
Objective We examined the association between plasma concentrations of high-sensitivity C-
reactive protein, soluble intercellular adhesion molecule 1, soluble E-selectin, angiotensin II …

高氧诱导小鼠视网膜新生血管模型中肾素(原) 受体表达及意义的研究

程钧, 董晓光, 谢立信, 万磊, 王晔 - 眼科新进展, 2010 - cqvip.com
目的探讨高氧诱导小鼠视网膜新生血管形成过程中肾素(原) 受体[(pro) renin receptor, PRR]
的表达和意义. 方法将新生C57BL/6J 小鼠随机分为2 组:(1) 对照组: 正常氧环境中饲养;(2) …

Biomarkers of inflammation, endothelial dysfunction and insulin resistance in adults of Inner Mongolia, China

G Wang, Y Liu, A Wang, W Tong… - … research and reviews, 2010 - Wiley Online Library
Background Low‐grade chronic inflammation and endothelial dysfunction have been
hypothesized to underlie the constellation of cardiometabolic risk factors, possibly by …

蒙古族人群血管紧张素Ⅱ 和肾素活性与高血压的危险性

焦阳, 彭颖, 汪桂艳, 佟伟军, 张永红 - 中华流行病学杂志, 2010 - cqvip.com
高血压是世界范围内的公共卫生问题. 炎症和内皮功能异常是动脉粥样硬化和心血管疾病的新
危险因素. 血管紧张素Ⅱ (AngⅡ) 不仅具有收缩血管的作用, 也可诱导内皮功能异常和炎症反应 …

[PDF][PDF] Wirkung von Valsartan und Fluvastatin auf den oxidativen Stress und die Synthese artherogener Zytokine bei Patienten mit koronarer Herzerkrankung

AH Fischer - 2010 - ediss.sub.uni-hamburg.de
2.1 Hintergrund Nach wie vor stellen Erkrankungen des kardiovaskulären Systems die
häufigste Todesursache der westlichen Nationen dar. Im Jahr 2007 erlag fast jeder zweite …