FtsZ, a bacterial homolog of tubulin, is well established as forming the cytoskeletal
framework for the cytokinetic ring. Recent work has shown that purified FtsZ, in the absence …

The emergence of multidrug-resistant Mycobacterium tuberculosis strains has made many of
the currently available anti-tuberculosis (TB) drugs ineffective. Accordingly, there is a …

The cytoskeletal protein, FtsZ plays a pivotal role in prokaryotic cell division and is present in
majority of the bacterial species. In recent years, inhibitors of FtsZ have been identified that …

Background Berberine is a plant alkaloid that is widely used as an anti-infective in traditional
medicine. Escherichia coli exposed to berberine form filaments, suggesting an antibacterial …

Eight new antimicrobial natural products named chrysophaentins A− H belonging to a new
structural class have been isolated from the marine chrysophyte alga Chrysophaeum taylori …

An efficient, convergent synthesis of totarol by a diastereoselective epoxide/alkene/arene
bicyclization is described. The reported synthesis enables the preparation of related …

PKC, β-arrestin 2, CARMA3, BCL10, MALT1, TRAF6 and MEKK3 are signaling proteins that
have a key role in G protein-coupled receptor (GPCR)-mediated activation of nuclear factor …

Staphylococcus causes a large number of animal and human diseases and has been
considered as a major health concern. With the emergence of resistant strains of …

Bacterial resistance to antibiotics, particularly to multiple antibiotics, is becoming a cause for
significant concern. The only really viable course of action to counter this is to discover new …

MATERIALS AND METHODS Purification of Edeine B1 Edeine B1 was isolated from a
culture filtrate of Bacillus brevis TTO2-8. The purified edeine B1 yielded a single TLC spot, a …