Chronic inflammation is associated with aging and plays a causative role in several age-
related diseases such as cancer, atherosclerosis and osteoarthritis. The source of this …

The innate immune system is composed of a network of cells including neutrophils, NK and
NKT cells, monocytes/macrophages, and dendritic cells that mediate the earliest interactions …

Background Age-related physiological changes in the gastrointestinal tract, as well as
modifications in lifestyle, nutritional behaviour, and functionality of the host immune system …

Systemic infection and drugs with anticholinergic effects are well-recognised and prevalent
risk factors for delirium in elderly people. Experimental findings and neuropathological …

Decoding Cell Death Signals in Inflammation and Immunity: Cell Skip to Main Content
Advertisement Cell This journal offers authors two options (open access or subscription) to …

We evaluated TLR function in primary human dendritic cells (DCs) from 104 young (age 21–
30 y) and older (≥ 65 y) individuals. We used multicolor flow cytometry and intracellular …

Concord grape juice contains polyphenol compounds, which have antioxidant and anti-
inflammatory properties and influence neuronal signalling. Concord grape juice …

The recent major increase in the global incidence of type 2 diabetes suggests that most
cases of this disease are caused by changes in environment and lifestyle. All major risk …

Background: About hundred years ago, Oskar Fischer proposed that the senile plaques are
the consequence of the deposition of a foreign substance that could induce an inflammatory …

Several inflammatory biomarkers appear to add to our ability to predict mortality or
opportunistic disease in HIV-infected individuals. Before biomarkers will be useful, it will be …