I Han, YM You, JH Kordower, ST Brady… - Journal of …, 2010 - Wiley Online Library
J. Neurochem.(2010) 113, 1073–1091. Abstract Abnormal expansion of a polyglutamine tract in huntingtin (Htt) protein results in Huntington's disease (HD), an autosomal dominant …
J Miller, M Arrasate, BA Shaby, S Mitra… - Journal of …, 2010 - Soc Neuroscience
An expanded polyglutamine (polyQ) stretch in the protein huntingtin (htt) induces self- aggregation into inclusion bodies (IBs) and causes Huntington's disease (HD). Defining …
BR Miller, I Bezprozvanny - Future neurology, 2010 - Taylor & Francis
Huntington's disease (HD) is a noncurable and progressive autosomal-dominant neurodegenerative disorder that results from a polyglutamine expansion in the amino …
[spa] En el desarrollo de esta tesis doctoral nos hemos centrado en el estudio de diferentes vías de señalización intracelular implicadas en los procesos de supervivencia y muerte …
Abstract Huntington's disease (HD), an adult-onset, dominantly-inherited neurodegenerative disease primarily affecting the striatum and deep cortical regions of the brain, is caused by a …