With nonalcoholic steatohepatitis (NASH), NASH cirrhosis, and NASH-related hepatocellular
carcinoma becoming increasingly prevalent, the need for effective therapies has never been …

Jones DP (Department of Medicine, Emory University, Atlanta, GA, USA). Redox sensing:
orthogonal control in cell cycle and apoptosis signalling (Symposium). J Intern Med 2010; …

Reactive oxygen species (ROS) and reactive nitrogen species have generally been
considered as being highly reactive and cytotoxic molecules. Besides their noxious effects …

Decreased expression and/or activity of antioxidant proteins leads to oxidative stress,
accelerated aging, and neurodegeneration. While overwhelming levels and uncontrolled …

Limited amounts of reactive oxygen species are necessary for cell survival and signaling,
but their excess causes oxidative stress. H2O2 and other reactive oxygen species are …

It has become clear in recent decades that the post-translational modification of protein
cysteine residues is a crucial regulatory event in biology. Evidence supports the reversible …

Src-family kinases are vitally important to the regulation of cytoskeleton organization, cell
proliferation, and the generation of integrin-dependent signaling responses, inducing …

Rationale: Nuclear factor erythroid 2-related factor (Nrf) 3, a member of the cap 'N'collar
family of transcription factors that bind to the DNA-antioxidant responsive elements, is …

The beneficial health effects of (−)-epigallocatechin-3-gallate (EGCG), the main catechin of
green tea, have been attributed to complex interactions with a focus on antioxidative …

Radiation therapy is in the front line for treatment of localized prostate cancer. However, a
significant percentage of patients have radiation‐resistant disease. The NF‐κB pathway is …