Remote ischemic preconditioning in human coronary artery bypass surgery: from promise to disappointment?

IA Rahman, JG Mascaro, RP Steeds, MP Frenneaux… - Circulation, 2010 - Am Heart Assoc
Background—We assessed whether remote ischemic preconditioning (RIPC) improves
myocardial, renal, and lung protection after on-pump coronary surgery. Methods and Results …

Ischaemic preconditioning improves proteasomal activity and increases the degradation of δPKC during reperfusion

EN Churchill, JC Ferreira, PC Brum… - Cardiovascular …, 2010 - academic.oup.com
Aims The response of the myocardium to an ischaemic insult is regulated by two highly
homologous protein kinase C (PKC) isozymes, δ and εPKC. Here, we determined the spatial …

Is there a place for cerebral preconditioning in the clinic?

RF Keep, MM Wang, J Xiang, Y Hua, G Xi - Translational stroke research, 2010 - Springer
Preconditioning (PC) describes a phenomenon whereby a sub-injury-inducing stress can
protect against a later injurious stress. Great strides have been made in identifying the …

Activation of cardiac muscarinic M3 receptors induces delayed cardioprotection by preserving phosphorylated connexin43 and up‐regulating cyclooxygenase‐2 …

J Zhao, Y Su, Y Zhang, Z Pan, L Yang… - British journal of …, 2010 - Wiley Online Library
Background and purpose: Activation of muscarinic M3 mucarinic acetylcholine receptors
(M3‐mAChRs) has been previously shown to confer short‐term cardioprotection against …

Attenuation of infarction in cynomolgus monkeys: preconditioning and postconditioning

XM Yang, Y Liu, Y Liu, N Tandon, J Kambayashi… - Basic research in …, 2010 - Springer
Ischemic pre-(IPC) and post-(IPOC) conditioning are very protective in laboratory animals,
but it has not been possible to measure their anti-infarct potency in human hearts. Non …

[HTML][HTML] Genetically determined angiotensin converting enzyme level and myocardial tolerance to ischemia

E Messadi, MP Vincent, V Griol-Charhbili… - The FASEB …, 2010 - ncbi.nlm.nih.gov
Angiotensin I-converting enzyme (ACE; kininase II) levels in humans are genetically
determined. ACE levels have been linked to risk of myocardial infarction, but the association …

[HTML][HTML] A novel category of anti-hypertensive drugs for treating salt-sensitive hypertension on the basis of a new development concept

M Katori, M Majima - Pharmaceuticals, 2010 - mdpi.com
Terrestrial animals must conserve water and NaCl to survive dry environments. The kidney
reabsorbs 95% of the sodium filtered from the glomeruli before sodium reaches the distal …

[HTML][HTML] Молекулярные механизмы ишемического и фармакологического прекондиционирования

ИВ Зарубина, АВ Горяинов… - Обзоры по клинической …, 2010 - cyberleninka.ru
В обзоре рассматривается действие кратковременных ишемических эпизодов в рамках
понятия ишемического раннего и позднего прекондиционирования (ИП), его …

[HTML][HTML] Escore eletrocardiografico: aplicacao em ergometria para avaliacao do precondicionamento isquemico

A Uchida, P Moffa, W Hueb, LAM Cesar… - Arquivos Brasileiros …, 2010 - SciELO Brasil
FUNDAMENTO: O tempo para 1, 0 mm de depressão do segmento ST (T-1, 0 mm), adotado
para caracterizar o precondicionamento isquêmico (PCI) em testes ergométricos …

Pretreatment by hyperoxia-a tool to reduce ischaemia-reperfusion injury in the myocardium

I Karu, P Tahepold, A Ruusalepp… - Current Clinical …, 2010 - ingentaconnect.com
Atherosclerosis leads to narrowing and occlusion of coronary arteries, resulting in
inadequate oxygen supply for maintenance of normal oxidative metabolism. To avoid …