Sex determination and disorders of sex development according to the revised nomenclature and classification in 46, XX individuals
E Kousta, A Papathanasiou, N Skordis - Hormones, 2010 - Springer
There have been considerable advances concerning understanding of the early and later
stages of ovarian development; a number of genes have been implicated and their …
stages of ovarian development; a number of genes have been implicated and their …
Variants of the BMP15 gene in a cohort of patients with premature ovarian failure
D Tiotiu, B Alvaro Mercadal, R Imbert… - Human …, 2010 - academic.oup.com
BACKGROUND Bone morphogenetic protein 15 (BMP15) is an oocyte-derived growth factor
acting as a major player in follicle differentiation in mammals. Mutations in the BMP15 gene …
acting as a major player in follicle differentiation in mammals. Mutations in the BMP15 gene …
Expression of GDF-9, BMP-15 and their receptors in mammalian ovary follicles
RZ Sun, L Lei, L Cheng, ZF Jin, SJ Zu, ZY Shan… - Journal of molecular …, 2010 - Springer
The synergetic process of folliculogenesis is mainly regulated by GDF-9 and BMP-15 as well
as their receptors, such as BMPR2, TβR1 and BMPR1B. Expressions of these factors and …
as their receptors, such as BMPR2, TβR1 and BMPR1B. Expressions of these factors and …
Similar phenotype characteristics comparing familial and sporadic premature ovarian failure
F Janse, EAH Knauff, MF Niermeijer, MJ Eijkemans… - Menopause, 2010 - journals.lww.com
Objective: Premature ovarian failure (POF) is characterized by secondary amenorrhea
before the age of 40 years, along with repeated increased follicle-stimulating hormone and …
before the age of 40 years, along with repeated increased follicle-stimulating hormone and …
Impaired production of BMP-15 and GDF-9 mature proteins derived from proproteins WITH mutations in the proregion
K Inagaki, S Shimasaki - Molecular and cellular endocrinology, 2010 - Elsevier
Mutations in the bone morphogenetic protein-15 (BMP-15) and growth and differentiation
factor-9 (GDF-9) genes have been identified in women with primary ovarian insufficiency …
factor-9 (GDF-9) genes have been identified in women with primary ovarian insufficiency …
Novel single-nucleotide polymorphisms of LHX8 gene in Korean women with premature ovarian insufficiency
S Jeon, HJ Won, YS Kim, SW Lyu, HH Seok, NK Kim… - Genes & Genomics, 2010 - Springer
Abstract LHX8 (LIM homeobox 8) is a germ cell-specific transcription factor that is crucial for
folliculogenesis in the ovary and represents a candidate gene for premature ovarian …
folliculogenesis in the ovary and represents a candidate gene for premature ovarian …
[引用][C] BMP15 and premature ovarian failure: causal mutations, variants, polymorphisms?
2 Sathyapalan, T., Cho, LW, Kilpatrick, ES et al.(2009) Metformin maintains the weight loss
and metabolic benefits following rimonabant treatment in obese women with polycystic …
and metabolic benefits following rimonabant treatment in obese women with polycystic …