Lassa virus (LASV), the causative agent of Lassa fever (LF), is endemic in West Africa,
accounting for substantial morbidity and mortality. In spite of ongoing research efforts, LF …

The method of choice for the detection of Lassa virus is reverse transcription (RT)-PCR.
However, the high degree of genetic variability of the virus poses a problem with the design …

We recently discovered a novel hantavirus, Sangassou virus, in Guinea, West Africa. Using
enzyme-linked immunosorbent assays followed by confirmatory and serotyping assays, we …

The epithelium plays a key role in the spread of Lassa virus. Transmission from rodents to
humans occurs mainly via inhalation or ingestion of droplets, dust, or food contaminated with …

The central domain of the 200-kDa Lassa virus L protein is a putative RNA-dependent RNA
polymerase. N-and C-terminal domains may harbor enzymatic functions important for viral …

To determine the specificity of Morogoro virus for its reservoir host, we studied its host range
and genetic diversity in Tanzania. We found that 2 rodent species other than Mastomys …

As part of a large survey on reservoirs of Lassa fever in Guinea, three villages were
investigated in high endemic zone, close to Sierra Leone border. Biodiversity of the small …

Wildlife surveys rely on an accurate taxonomic framework. Identification tools used to reach
this goal are not equivalent and may depend on several objectives and constraints …

By suppressing recombination and reducing gene flow, chromosome inversions favor the
capture and protection of advantageous allelic combinations, leading to adaptive …

Arenaviruses are usually rodent-borne viruses that constitute a major threat for human
health. Among them, Lassa Fever Virus (LFV) occurs in Western Africa where it infects …