Vaccines represent a special class of drugs, capable of stimulating immune system
responses against pathogens and tumors. Vaccine development is a lengthy process that …

Currently, cancer is one of the leading causes of death in industrial nations. While
conventional cancer treatment usually results in the patient suffering from severe side …

Using one of the well known mathematical models for immunotherapy of tumor–immune
interactions, in this paper an algorithm is developed to optimize the immunotherapy in …

Intra-patient variability is a key challenge in cancer treatment. This makes it necessary to find
the factors affecting tumor growth and accordingly schedule therapies over the treatment …

The mathematical model depicting cancer remission as presented by Banerjee and Sarkar1
is reinvestigated here. Mathematical tools from control theory have been used to analyze …

This thesis focuses on generating a continuous estimate of state using a small number of
sensors for a process modeled by the diffusion partial differential equation (PDE). In …

The use of combined therapies to treat cancer is common nowadays and some papers
already addressed the relative optimization problems. In particular, it is natural to have state …

Publisher Summary This chapter appraises the use of mathematical modeling to enhance
drug discovery and development for several diseases characterized by dysfunction of the …