Vascular pathophysiology in response to increased heart rate

F Custodis, SH Schirmer, M Baumhäkel… - Journal of the American …, 2010 - jacc.org
This review summarizes the current literature and the open questions regarding the
physiology and pathophysiology of the mechanical effects of heart rate on the vessel wall …

[PDF][PDF] Flow and atherosclerosis in coronary bifurcations

GD Giannoglou, AP Antoniadis, KC Koskinas… - EuroIntervention, 2010 - unmc.edu
Coronary bifurcations are among the most frequent sites affected by atherosclerosis. In
these regions, complex haemodynamic conditions prevail and local flow disturbances …

Natural history of experimental coronary atherosclerosis and vascular remodeling in relation to endothelial shear stress: a serial, in vivo intravascular ultrasound study

KC Koskinas, CL Feldman, YS Chatzizisis… - Circulation, 2010 - Am Heart Assoc
Background—The natural history of heterogeneous atherosclerotic plaques and the role of
local hemodynamic factors throughout their development are unknown. We performed a …

Elevated heart rate and cardiovascular outcomes in patients with coronary artery disease: clinical evidence and pathophysiological mechanisms

CC Lang, S Gupta, P Kalra, B Keavney, I Menown… - Atherosclerosis, 2010 - Elsevier
There is an established body of evidence from epidemiological studies which indicates that
an elevated resting heart rate is independently associated with atherosclerosis and …

Vortex formation and recirculation zones in left anterior descending artery stenoses: computational fluid dynamics analysis

DG Katritsis, A Theodorakakos, I Pantos… - Physics in Medicine …, 2010 - iopscience.iop.org
Flow patterns may affect the potential of thrombus formation following plaque rupture.
Computational fluid dynamics (CFD) were employed to assess hemodynamic conditions …

Prognostic clinical and angiographic characteristics for the development of a new significant lesion in remote segments after successful percutaneous coronary …

E Tsiamis, K Toutouzas, A Synetos… - International journal of …, 2010 - Elsevier
BACKGROUND: The majority of cardiovascular events in patients undergoing PCI arise from
the progression of NCL during the long-term follow-up period. The purpose of the study was …

[HTML][HTML] Systems biology in heart diseases

GE Louridas, IE Kanonidis, KG Lourida - Hippokratia, 2010 - ncbi.nlm.nih.gov
Abstract Systems biology based on integrative computational analysis and high technology
is in a position to construct networks, to study the interactions between molecular …

Shear stress and inflammation: are we getting closer to the prediction of vulnerable plaque?

YS Chatzizisis, GD Giannoglou - Expert review of cardiovascular …, 2010 - Taylor & Francis
Low ESS upregulates the expression of several adhesion molecules, chemoattractant
chemokines and proinflammatory cytokines [1, 9]. Adhesion molecules are expressed by …

基于CT 成像的冠状动脉流固耦合分析

钱秀清, 张晓慧, 王燕, 李宇, 刘志成 - 北京生物医学工程, 2010 - cqvip.com
目的基于冠状动脉血管弹性特征, 研究冠状动脉管壁及其内部血液流动的各力学参数的变化规律
. 方法根据健康人体冠状动脉造影的CT 图像, 用Mimics 软件三维重建冠状动脉多分支结构; …

A study of Quantification of Aortic Compliance in Mice using Radial Acquisition Phase Contrast MRI

X Zhao - 2010 - rave.ohiolink.edu
Spatiotemporal changes in blood flow velocity measured using Phase contrast Magnetic
Resonance Imaging (MRI) can be used to quantify Pulse Wave Velocity (PWV) and Wall …