Antiphospholipid syndrome

G Ruiz-Irastorza, M Crowther, W Branch… - The Lancet, 2010 - thelancet.com
The antiphospholipid syndrome causes venous, arterial, and small-vessel thrombosis;
pregnancy loss; and preterm delivery for patients with severe pre-eclampsia or placental …

The implications of autoimmunity and pregnancy

AT Borchers, SM Naguwa, CL Keen… - Journal of autoimmunity, 2010 - Elsevier
There are multiple epidemiological studies that document the potential adverse affects of
autoimmunity on nearly every aspect of reproduction, even in the absence of clinically …

The annexin A5-mediated pathogenic mechanism in the antiphospholipid syndrome: role in pregnancy losses and thrombosis

JH Rand, XX Wu, AS Quinn, DJ Taatjes - Lupus, 2010 - journals.sagepub.com
Annexin A5 (AnxA5) binds to phospholipid bilayers, forming two-dimensional crystals that
block the phospholipids from availability for coagulation enzyme reactions. Antiphospholipid …

Challenges in the diagnosis of the antiphospholipid syndrome

K Devreese, MF Hoylaerts - Clinical chemistry, 2010 - academic.oup.com
Background: The antiphospholipid syndrome (APS) is an important cause of acquired
thromboembolic complications and pregnancy morbidity. Its diagnosis is based on clinical …

[HTML][HTML] Analytical and clinical performance of a new, automated assay panel for the diagnosis of antiphospholipid syndrome

P De Moerloose, G Reber, J Musial, J Arnout - Journal of Thrombosis and …, 2010 - Elsevier
Background: Anticardiolipin (aCL) and anti‐β 2 glycoprotein I (aβ 2 GPI) antibodies are part
of the criteria for antiphospholipid syndrome (APS). Therefore they are widely measured and …

Antiphospholipid syndrome: critical analysis of the diagnostic path

V Pengo, A Banzato, E Bison, G Denas… - Lupus, 2010 - journals.sagepub.com
Antiphospholipid syndrome (APS) is diagnosed in the presence of vascular thrombosis or
pregnancy morbidity occurring in patients with circulating antiphospholipid antibodies (lupus …

A novel dimeric inhibitor targeting Beta2GPI in Beta2GPI/antibody complexes implicated in antiphospholipid syndrome

A Kolyada, CJ Lee, A De Biasio, N Beglova - PLoS One, 2010 - journals.plos.org
Background β2GPI is a major antigen for autoantibodies associated with antiphospholipid
syndrome (APS), an autoimmune disease characterized by thrombosis and recurrent …

Chemical synthesis and characterization of wild‐type and biotinylated N‐terminal domain 1–64 of β2‐glycoprotein I

N Pozzi, A Banzato, S Bettin, E Bison, V Pengo… - Protein …, 2010 - Wiley Online Library
The antiphospholipid syndrome (APS) is a severe autoimmune disease associated with
recurrent thrombosis and fetal loss and characterized by the presence of circulating …

[HTML][HTML] The antiphospholipid triangle

M Galli - Journal of Thrombosis and Haemostasis, 2010 - Elsevier
The antiphospholipid triangle - ScienceDirect Skip to main contentSkip to article Elsevier
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Antiphospholipidsyndrom

GMA van Os, RT Urbanus, C Agar… - …, 2010 - thieme-connect.com
The antiphospholipid syndrome (APS) is a non-inflammatory autoimmune disease
characterized by the presence of antiphospholipid antibodies (aPL) in the plasma of patients …