While virtually absent in our diet a few hundred years ago, fructose has now become a major
constituent of our modern diet. Our main sources of fructose are sucrose from beet or cane …

Nonalcoholic fatty liver disease (NAFLD) is the most frequent liver disease worldwide, and is
commonly associated with the metabolic syndrome. Secular trends in the prevalence of …

As dietary exposure to fructose has increased over the past 40 years, there is growing
concern that high fructose consumption in humans may be in part responsible for the rising …

There has been much concern regarding the role of dietary fructose in the development of
metabolic diseases. This concern arises from the continuous increase in fructose (and total …

Rates of fructose consumption continue to rise nationwide and have been linked to rising
rates of obesity, type 2 diabetes, and metabolic syndrome. Because obesity has been …

AIMS: The present study aimed to assess the effects of excess fat, fructose and fat-plus-
fructose intakes on intrahepatocellular lipid (IHCL). METHODS: Healthy male subjects were …

Consumption of simple carbohydrates has markedly increased over the past decades, and
may be involved in the increased prevalence in metabolic diseases. Whether an increased …

High consumption of dietary fructose is an important contributory factor in the development
of hepatic steatosis in insulin or leptin resistance. We investigated the effects of curcumin on …

Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the metabolic
syndrome, whose pathogenesis begins with the accumulation of liver fat and is followed by …

Growing evidence links the three mammalian lipin proteins, ie, lipin-1, lipin-2 and lipin-3, to
metabolic and cardiovascular diseases such as noninsulin-dependent diabetes mellitus and …