Ouabain-induced perturbations in intracellular ionic homeostasis regulate death receptor-mediated apoptosis

MI Panayiotidis, R Franco, CD Bortner, JA Cidlowski - Apoptosis, 2010 - Springer
Apoptosis is defined by specific morphological and biochemical characteristics including cell
shrinkage (termed apoptotic volume decrease), a process that results from the regulation of …

Evaluation of the electron transport chain inhibition and uncoupling of mitochondrial bioelectrocatalysis with antibiotics and nitro-based compounds

MN Arechederra, CN Fischer, DJ Wetzel, SD Minteer - Electrochimica Acta, 2010 - Elsevier
Mitochondrial bioelectrocatalysis can be useful for sensing applications due to the unique
metabolic pathways than can be selectively inhibited and uncoupled in mitochondria. This …

Cardiotonic steroid-resistant α1-Na+,K+-ATPase rescues renal epithelial cells from the cytotoxic action of ouabain: evidence for a Na i + ,K i …

OA Akimova, J Tremblay, JW Van Huysse, P Hamet… - Apoptosis, 2010 - Springer
Mechanisms underlying the tissue-specific impact of cardiotonic steroids (CTS) on cell
survival and death remain poorly understood. This study examines the role of Na+, K+ …

Diverse actions of ouabain and its aglycone ouabagenin in renal cells

RC Valente, LS Capella, MMM Oliveira… - Cell biology and …, 2010 - Springer
The cellular actions of ouabain are complex and involve different pathways, depending on
the cell type and experimental conditions. Several studies have reported that Madin–Darby …

Investigation of mechanism of p38 MAPK activation in renal epithelial cell from distal tubules triggered by cardiotonic steroids

OA Akimova, OD Lopina, AM Rubtsov, P Hamet… - Biochemistry …, 2010 - Springer
Ouabain and other cardiotonic steroids (CTS) kill renal epithelial cells from distal tubules
(C7-MDCK) via interaction with Na, K-ATPase but independently of inhibition of Na, K …

Исследование механизма активации р38 MAPK кардиотоническими стероидами в клетках эпителия дистального отдела почечных канальцев (ускоренная …

ОА Акимова, ОД Лопина, АМ Рубцов, П Хамет… - Биохимия, 2010 - elibrary.ru
Уабаин и другие кардиотонические стероиды (КТС) вызывают гибель клеток эпителия
дистального отдела почечных канальцев (С7-MDCK) путем взаимодействия с Na, К …