The environment and schizophrenia

J Van Os, G Kenis, BPF Rutten - Nature, 2010 - nature.com
Psychotic syndromes can be understood as disorders of adaptation to social context.
Although heritability is often emphasized, onset is associated with environmental factors …

Adolescent cannabis use and psychosis: epidemiology and neurodevelopmental models

DT Malone, MN Hill, T Rubino - British journal of pharmacology, 2010 - Wiley Online Library
Cannabis is one of the most widely used illicit drugs among adolescents, and most users
first experiment with it in adolescence. Adolescence is a critical phase for brain …

[图书][B] Cannabis policy: Moving beyond stalemate

R Room - 2010 - books.google.com
Cannabis, marijuana, pot, ganja-it goes by many names-is by far the most widely used
illegal substance, and accounts for more arrests than any other drug. Barely a week goes by …

Neuropsychological consequences of alcohol and drug abuse on different components of executive functions

MJ Fernandez-Serrano… - Journal of …, 2010 - journals.sagepub.com
Several studies have shown alterations in different components of executive functioning in
users of different drugs, including cannabis, cocaine and heroin. However, it is difficult to …

Neuroimaging in cannabis use: a systematic review of the literature

R Martin-Santos, AB Fagundo, JA Crippa… - Psychological …, 2010 - cambridge.org
BackgroundWe conducted a systematic review to assess the evidence for specific effects of
cannabis on brain structure and function. The review focuses on the cognitive changes …

Hippocampal and caudate volume reductions in antipsychotic-naive first-episode schizophrenia

BH Ebdrup, B Glenthøj, H Rasmussen… - Journal of Psychiatry and …, 2010 - jpn.ca
Background: Enlarged ventricles and reduced hippocampal volume are consistently found
in patients with first-episode schizophrenia. Studies investigating brain structure in …

Does dopamine mediate the psychosis-inducing effects of cannabis? A review and integration of findings across disciplines

R Kuepper, PD Morrison, J van Os, RM Murray… - Schizophrenia …, 2010 - Elsevier
General population epidemiological studies have consistently found that cannabis use
increases the risk of developing psychotic disorders in a dose-dependent manner. While the …

Neurochemistry of drug action: insights from proton magnetic resonance spectroscopic imaging and their relevance to addiction

SC Licata, PF Renshaw - Annals of the New York Academy of …, 2010 - Wiley Online Library
Proton magnetic resonance spectroscopy (1H MRS) is a noninvasive imaging technique that
permits measurement of particular compounds or metabolites within the tissue of interest. In …

Hippocampal pathology in individuals at ultra-high risk for psychosis: a multi-modal magnetic resonance study

SJ Wood, D Kennedy, LJ Phillips, ML Seal, M Yücel… - Neuroimage, 2010 - Elsevier
Although the hippocampus is a key brain region in the pathophysiology of schizophrenia, it
is unclear whether structural or biochemical abnormalities predate illness onset. In this …

Structural MRI findings in long-term cannabis users: what do we know?

V Lorenzetti, DI Lubman, S Whittle… - Substance use & …, 2010 - Taylor & Francis
In animal studies, tetrahydrocannabinol (THC) has been found to affect brain morphology,
particularly within areas rich in cannabinoid receptors (eg, hippocampus, cerebral cortex) …