Central role of the brain in stress and adaptation: links to socioeconomic status, health, and disease

BS McEwen, PJ Gianaros - Annals of the New York Academy of …, 2010 - Wiley Online Library
The brain is the key organ of stress reactivity, coping, and recovery processes. Within the
brain, a distributed neural circuitry determines what is threatening and thus stressful to the …

The role of BDNF and its receptors in depression and antidepressant drug action: reactivation of developmental plasticity

E Castrén, T Rantamäki - Developmental neurobiology, 2010 - Wiley Online Library
Recent evidence suggests that neuronal plasticity plays an important role in the recovery
from depression. Antidepressant drugs and electroconvulsive shock treatment increase the …

Towards a neural basis of music-evoked emotions

S Koelsch - Trends in cognitive sciences, 2010 - cell.com
Music is capable of evoking exceptionally strong emotions and of reliably affecting the mood
of individuals. Functional neuroimaging and lesion studies show that music-evoked …

Nuclear factor-κB is a critical mediator of stress-impaired neurogenesis and depressive behavior

JW Koo, SJ Russo, D Ferguson… - Proceedings of the …, 2010 - National Acad Sciences
Proinflammatory cytokines, such as IL-1β, have been implicated in the cellular and
behavioral effects of stress and in mood disorders, although the downstream signaling …

[HTML][HTML] The roles of BDNF in the pathophysiology of major depression and in antidepressant treatment

BH Lee, YK Kim - Psychiatry investigation, 2010 - ncbi.nlm.nih.gov
Neurotrophic factors are critical regulators of the formation and plasticity of neuronal
networks. Brain-derived neurotrophic factor (BDNF) is abundant in the brain and periphery …

A high-fat diet impairs neurogenesis: involvement of lipid peroxidation and brain-derived neurotrophic factor

HR Park, M Park, J Choi, KY Park, HY Chung, J Lee - Neuroscience letters, 2010 - Elsevier
Obesity is a growing global health problem that contributes to diabetes, hypertension,
cardiovascular diseases, dementia, and cancer. The increased consumption of saturated …

Regulation of adult neurogenesis by stress, sleep disruption, exercise and inflammation: Implications for depression and antidepressant action

PJ Lucassen, P Meerlo, AS Naylor, AM van Dam… - European …, 2010 - Elsevier
Adult hippocampal neurogenesis, a once unorthodox concept, has changed into one of the
most rapidly growing fields in neuroscience. The present report results from the ECNP …

Adult neurogenesis: integrating theories and separating functions

JB Aimone, W Deng, FH Gage - Trends in cognitive sciences, 2010 - cell.com
The continuous incorporation of new neurons in the dentate gyrus of the adult hippocampus
raises exciting questions about memory and learning, and has inspired new computational …

Decreased numbers of progenitor cells but no response to antidepressant drugs in the hippocampus of elderly depressed patients

PJ Lucassen, MW Stumpel, Q Wang, E Aronica - Neuropharmacology, 2010 - Elsevier
Imaging studies have consistently documented hippocampal volume reductions in
depression. Although depressive disorders are traditionally considered to have a …

Prolactin-induced mitogenesis in the subventricular zone of the maternal brain during early pregnancy is essential for normal postpartum behavioral responses in the …

CM Larsen, DR Grattan - Endocrinology, 2010 - academic.oup.com
High prolactin during pregnancy, which is essential for normal postpartum maternal
behavior, increases neurogenesis in the subventricular zone of the lateral ventricle (SVZ) of …