Marked changes in socio-economic status, cultural traditions, population growth and
agriculture are affecting diets worldwide. Understanding how our diet and nutritional status …

Recent advances have provided substantial insight into the maintenance of mucosal
immunity and the pathogenesis of inflammatory bowel disease. Cellular programs …

Background A critical output of metagenomic studies is the estimation of abundances of
taxonomical or functional groups. The inherent uncertainty in assignments to these groups …

The advent of next generation sequencing has coincided with a growth in interest in using
these approaches to better understand the role of the structure and function of the microbial …

Disease-suppressive soils are exceptional ecosystems in which crop plants suffer less from
specific soil-borne pathogens than expected owing to the activities of other soil …

Our knowledge of species and functional composition of the human gut microbiome is
rapidly increasing, but it is still based on very few cohorts and little is known about variation …

Inflammasomes are multiprotein complexes that function as sensors of endogenous or
exogenous damage-associated molecular patterns. Here, we show that deficiency of NLRP6 …

Bidirectional signalling between the gastrointestinal tract and the brain is regulated at
neural, hormonal, and immunological levels. This construct is known as the brain–gut axis …

To what extent do host genetics control the composition of the gut microbiome? Studies
comparing the gut microbiota in human twins and across inbred mouse lines have yielded …

OBJECTIVE To investigate deep and comprehensive analysis of gut microbial communities
and biological parameters after prebiotic administration in obese and diabetic mice …