The presence of glucose or other rapidly metabolizable carbon sources in the bacterial
growth medium strongly represses Clostridium difficile toxin synthesis independently of …

In Gram-positive bacteria, the transcriptional regulator CcpA is at the core of catabolite
control mechanisms. In the human pathogen Streptococcus pneumoniae, links between …

Streptococcus suis is one of the most important pathogens in pigs and is also an emerging
zoonotic agent. After crossing the epithelial barrier, S. suis causes bacteraemia, resulting in …

Polyamines such as cadaverine, putrescine and spermidine are polycationic molecules that
have pleiotropic effects on cells via their interaction with nucleic acids. Streptococcus …

Streptococcus pneumoniae is a major cause of pneumonia and meningitis. Airway
colonization is a necessary precursor to disease, but little is known about how the bacteria …

Streptococcus pneumoniae is the leading cause of community-acquired pneumonia and
results in over 1 million deaths each year worldwide. Asymptomatic colonization of the …

The genomic analysis of Streptococcus pneumoniae predicted six putative glutamine uptake
systems, which are expressed under in vitro conditions, as shown here by reverse …

Sensing environmental conditions is an essential aspect of bacterial physiology and
virulence. In Bacillus anthracis, the causative agent of anthrax, transcription of the two major …

Streptococcus gordonii is an important member of the oral biofilm. One of its phenotypic
traits is the production of hydrogen peroxide (H2O2). H2O2 is an antimicrobial component …

Type II (proteic) toxin-antitoxin systems (TAS) are ubiquitous among bacteria. In the
chromosome of the pathogenic bacterium Streptococcus pneumoniae, there are at least …