PAC1hop, null and hip receptors mediate differential signaling through cyclic AMP and calcium leading to splice variant-specific gene induction in neural cells

Y Holighaus, T Mustafa, LE Eiden - Peptides, 2011 - Elsevier
Pituitary adenylate cyclase-activating polypeptide (PACAP)-mediated activation of its G
protein-coupled receptor PAC1 results in activation of the two G proteins Gs and Gq to alter …

[HTML][HTML] Origin of secretin receptor precedes the advent of tetrapoda: evidence on the separated origins of secretin and orexin

JKV Tam, KW Lau, LTO Lee, JYS Chu, KM Ng… - PLoS …, 2011 - journals.plos.org
At present, secretin and its receptor have only been identified in mammals, and the origin of
this ligand-receptor pair in early vertebrates is unclear. In addition, the elusive similarities of …

Extragastrointestinal functions and transcriptional regulation of secretin and secretin receptors

Y Yuan, LTO Lee, SS Ng… - Annals of the New York …, 2011 - Wiley Online Library
The functional role of secretin outside the gastrointestinal system has been a mystery to
endocrinologists for many years. With the availability of secretin‐and secretin receptor …

[HTML][HTML] Secretin receptor

LJ Miller, M Dong - Pancreapedia: The Exocrine Pancreas …, 2011 - pancreapedia.org
Secretin and its receptor hold special places in history, with secretin representing the first
“hormone”, giving rise to the field of endocrinology when WM Bayliss and EH Starling …

The Mechanics of Arrestin–Receptor Interaction: How GPCRs and Arrestins Talk to Each Other

VV Gurevich, EV Gurevich - 2011 - books.rsc.org
335 specifically expressed in cones, although it constitutes only 2% of their total arrestin
complement. 5 Non-visual arrestin-2 (first described as β-arrestin) 6 and arrestin-37 (first …

Entwicklung von Secretin-und Glucagon-like peptide-2-Rezeptor-Antagonisten für die Tumordiagnostik

A Klußmeier - 2011 - refubium.fu-berlin.de
Die erfolgreiche Therapie einer Krebserkrankung ist häufig von einer rechtzeitigen
Diagnose und dem damit verbundenen rechtzeitigen Behandlungsbeginn abhängig. Eine …

Peptide Hormone Recognition in Class B GPCRs: Role of the Extracellular Domain in Receptor Activation

C Parthier, MT Stubbs - 2011 - books.rsc.org
Class B GPCRs comprise a family of receptors for a variety of therapeutically relevant
peptide hormones. Their activity is implicated in several pivotal biological processes …

[PDF][PDF] Origin of Secretin Receptor Precedes the Advent of Tetrapoda: Evidence on the Separated

JKV Tam, KW Lau, LTO Lee, JYS Chu, KM Ng - 2011 - academia.edu
At present, secretin and its receptor have only been identified in mammals, and the origin of
this ligand-receptor pair in early vertebrates is unclear. In addition, the elusive similarities of …