The PP2A regulatory subunit Tap46, a component of the TOR signaling pathway, modulates growth and metabolism in plants

CS Ahn, JA Han, HS Lee, S Lee, HS Pai - The Plant Cell, 2011 - academic.oup.com
Abstract Tap42/α4, a regulatory subunit of protein phosphatase 2A, is a downstream effector
of the target of rapamycin (TOR) protein kinase, which regulates cell growth in coordination …

Concentration of antifungal agents within host cell membranes: a new paradigm governing the efficacy of prophylaxis

P Campoli, Q Al Abdallah, R Robitaille… - Antimicrobial agents …, 2011 - Am Soc Microbiol
Posaconazole prophylaxis has proven highly effective in preventing invasive fungal
infections, despite relatively low serum concentrations. However, high tissue levels of this …

Activity of the Ste20-like kinase, SLK, is enhanced by homodimerization

S Delarosa, J Guillemette, J Papillon… - American Journal …, 2011 - journals.physiology.org
The expression and activation of the Ste20-like kinase, SLK, is increased during renal
development and recovery from ischemic acute renal failure. SLK promotes apoptosis, and …

Overexpression of immunoglobulin (CD79a) binding protein1 (IGBP‐1) in small lung adenocarcinomas and its clinicopathological significance

S Sakashita, D Li, N Nashima, Y Minami… - Pathology …, 2011 - Wiley Online Library
Immunoglobulin binding protein 1 (IGBP‐1) was initially identified as a signal transduction
molecule coprecipitating with MB1 (Igα) of the B cell antigen receptor (BCR) complex and …

[图书][B] Characterising the signalling mechanism of the mTOR-dependent phosphatase

LA Seymour - 2011 - search.proquest.com
Abstract The mechanistic Target of Rapamycin Complex 1 (mTORC1) complex is central in
the regulation of many crucial cellular processes including translation, transcription …