S Chalbot, H Zetterberg, K Blennow… - Journal of …, 2011 - content.iospress.com
The role of blood-cerebrospinal fluid barrier (BCB) dysfunction in Alzheimer's disease (AD) has been addressed but not yet established. We evaluated the BCB integrity in 179 samples …
SM Rauch, K Huen, MC Miller… - … of Neuropathology & …, 2011 - academic.oup.com
Conditions that compromise the blood-brain barrier (BBB) have been increasingly implicated in the pathogenesis of Alzheimer disease (AD). AGRIN is a heparan sulfate …
V Lam, R Takechi, MMS Pallebage-Gamarallage… - Neuroscience …, 2011 - Elsevier
Alzheimer's disease (AD) is characterized by cerebral proteinaceous deposits comprised of amyloid beta (Aβ). Evidence suggests that enhanced blood-to-brain delivery of Aβ occurs …
T Hosono‐Fukao, S Ohtake‐Niimi… - Journal of …, 2011 - Wiley Online Library
RB4CD12 is a phage display antibody that recognizes a heparan sulfate (HS) glycosaminoglycan epitope. The epitope structure is proposed to contain a trisulfated …
We previously demonstrated a differential expression pattern of several HSPG subtypes in AD lesions [254, 255, 257]. Unlike the syndecans, perlecans and collagen XVIII, the HSPG …
RA Cohen - Brain imaging in behavioral medicine and clinical …, 2011 - Springer
Cardiovascular disease (CVD) remains the leading cause of death in this country, underlying over 700,000 deaths per year (American Heart Association. Cardiovascular …