Casting a net on dendritic spines: the extracellular matrix and its receptors

LE Dansie, IM Ethell - Developmental neurobiology, 2011 - Wiley Online Library
Dendritic spines are dynamic structures that accommodate the majority of excitatory
synapses in the brain and are influenced by extracellular signals from presynaptic neurons …

Blood-cerebrospinal fluid barrier permeability in Alzheimer's disease

S Chalbot, H Zetterberg, K Blennow… - Journal of …, 2011 - content.iospress.com
The role of blood-cerebrospinal fluid barrier (BCB) dysfunction in Alzheimer's disease (AD)
has been addressed but not yet established. We evaluated the BCB integrity in 179 samples …

Changes in Brain β-Amyloid Deposition and Aquaporin 4 Levels in Response to Altered Agrin Expression in Mice

SM Rauch, K Huen, MC Miller… - … of Neuropathology & …, 2011 - academic.oup.com
Conditions that compromise the blood-brain barrier (BBB) have been increasingly
implicated in the pathogenesis of Alzheimer disease (AD). AGRIN is a heparan sulfate …

Colocalisation of plasma derived apo B lipoproteins with cerebral proteoglycans in a transgenic-amyloid model of Alzheimer's disease

V Lam, R Takechi, MMS Pallebage-Gamarallage… - Neuroscience …, 2011 - Elsevier
Alzheimer's disease (AD) is characterized by cerebral proteinaceous deposits comprised of
amyloid beta (Aβ). Evidence suggests that enhanced blood-to-brain delivery of Aβ occurs …

RB4CD12 epitope expression and heparan sulfate disaccharide composition in brain vasculature

T Hosono‐Fukao, S Ohtake‐Niimi… - Journal of …, 2011 - Wiley Online Library
RB4CD12 is a phage display antibody that recognizes a heparan sulfate (HS)
glycosaminoglycan epitope. The epitope structure is proposed to contain a trisulfated …

[图书][B] The interaction of heparan sulfate proteoglycans with the amyloid β protein.

NM Timmer - 2011 - repository.ubn.ru.nl
We previously demonstrated a differential expression pattern of several HSPG subtypes in
AD lesions [254, 255, 257]. Unlike the syndecans, perlecans and collagen XVIII, the HSPG …

Neuroimaging of cardiovascular disease

RA Cohen - Brain imaging in behavioral medicine and clinical …, 2011 - Springer
Cardiovascular disease (CVD) remains the leading cause of death in this country,
underlying over 700,000 deaths per year (American Heart Association. Cardiovascular …