Pericytes are uniquely positioned within the neurovascular unit to serve as vital integrators,
coordinators and effectors of many neurovascular functions, including angiogenesis, blood …

Myocardial TGF-β expression is upregulated in experimental models of myocardial infarction
and cardiac hypertrophy, and in patients with dilated or hypertrophic cardiomyopathy …

Pericytes are branched cells embedded within the basement membrane of capillaries and
post-capillary venules. They provide an incomplete investment to endothelial cells, thus …

Emerging evidence indicates that angiogenesis and immunosuppression frequently occur
simultaneously in response to diverse stimuli. Here, we describe a fundamental biological …

Tumorigenesis is in many respects a process of dysregulated cellular evolution that drives
malignant cells to acquire six phenotypic hallmarks of cancer, including their ability to …

Control over cell engraftment, survival, and function remains critical for heart repair. We have
established a tissue engineering platform for the delivery of human mesenchymal progenitor …

It is becoming increasingly clear that members of the transforming growth factor-β (TGF-β)
family have roles in the central nervous system that extend beyond their well-established …

Transforming growth factor-β (TGF-β) is a multifunctional cytokine that functions to inhibit
mammary tumorigenesis by directly inducing mammary epithelial cells (MECs) to undergo …

Connective tissue growth factor (CCN2) is a multifunctional matricellular protein, which is
frequently overexpressed during organ fibrosis. CCN2 is a mediator of the pro-fibrotic effects …

Cyclical formation and regression of the ovarian corpus luteum is required for reproduction.
During luteal regression, the microvasculature of the corpus luteum is extensively disrupted …