Receptor mediated tumor targeting: an emerging approach for cancer therapy

C Mohanty, M Das, JR Kanwar… - Current drug …, 2011 - ingentaconnect.com
Receptor-mediated tumor targeting has received major attention in the field of cancer drug
delivery in the past few years. Receptors, as molecular target has opened new opportunities …

Image‐guided prostate cancer therapy using aptamer‐functionalized thermally cross‐linked superparamagnetic iron oxide nanoparticles

MK Yu, D Kim, IH Lee, JS So, YY Jeong, S Jon - Small, 2011 - Wiley Online Library
CG‐rich duplex containing prostate‐specific membrane antigen (PSMA) aptamer‐
conjugated thermally cross‐linked superparamagnetic iron oxide nanoparticles (TCL …

Diagnostic and therapeutic use of membrane proteins in cancer cells

D Grimm, J Bauer, J Pietsch, M Infanger… - Current medicinal …, 2011 - ingentaconnect.com
As proteomics technologies develop, increasing number of membrane-associated proteins
specific for cancer cells are being discovered. These proteins are of great interest …

Prostate-specific membrane antigen as a potential novel vascular target for treatment of glioblastoma multiforme

AG Wernicke, MA Edgar, E Lavi… - … of pathology & …, 2011 - meridian.allenpress.com
Context.—Prostate-specific membrane antigen (PSMA) is expressed in endothelium of
vessels in malignant solid tumors but not in normal vessels. Objective.—To examine …

Detection of prostate-specific membrane antigen on HUVECs in response to breast tumor-conditioned medium

T Liu, M Jabbes, JR Nedrow-Byers… - International …, 2011 - spandidos-publications.com
Prostate-specific membrane antigen (PSMA), a well-known biomarker of prostate cancer,
has also been found to be highly expressed in the neovasculature of multiple non-prostatic …

Spacer length effects on in vitro imaging and surface accessibility of fluorescent inhibitors of prostate specific membrane antigen

T Liu, JR Nedrow-Byers, MR Hopkins… - Bioorganic & medicinal …, 2011 - Elsevier
Prostate-specific membrane antigen (PSMA), a type II transmembrane protein, has been
becoming an active target for imaging and therapeutic applications for prostate cancer …

[HTML][HTML] Molecular identification of β-citrylglutamate hydrolase as glutamate carboxypeptidase 3

F Collard, D Vertommen, S Constantinescu… - Journal of Biological …, 2011 - ASBMB
β-Citrylglutamate (BCG), a compound present in adult testis and in the CNS during the pre-
and perinatal periods is synthesized by an intracellular enzyme encoded by the RIMKLB …

Diagnostic and therapeutic imaging for cancer: therapeutic considerations and future directions

M Roach III, JL Alberini, AP Pecking… - Journal of surgical …, 2011 - Wiley Online Library
As cancer treatment cost soar and the mantra for “personalized medicine” grows louder, we
will increasingly be searching for solutions to these diametrically opposed forces. In this …

[HTML][HTML] Prostate specific membrane antigen as biomarker and therapeutic target for prostate cancer

P Wolf, PE Spiess - Prostate Cancer-Diagnostic and Therapeutic …, 2011 - books.google.com
The Prostate Specific Membrane Antigen (PSMA) is considered to be the most well
established target antigen in prostate cancer, since it is highly and specifically expressed at …

Glutamate carboxypeptidase II as a therapeutic target

K Hlouchová, C BaŘinka… - Proteinases as Drug …, 2011 - books.google.com
Glutamate carboxypeptidase II (GCPII; EC 3.4. 17.21), a Zn2+-dependent metalloprotease of
the M28 peptidase family, is a type II transmembrane glycoprotein. GCPII is also known as …