Polysialic acid controls NCAM signals at cell–cell contacts to regulate focal adhesion independent from FGF receptor activity
K Eggers, S Werneburg, A Schertzinger… - Journal of cell …, 2011 - journals.biologists.com
The polysialic acid (polySia) modification of the neural cell adhesion molecule NCAM is a
key regulator of cell migration. Yet its role in NCAM-dependent or NCAM-independent …
key regulator of cell migration. Yet its role in NCAM-dependent or NCAM-independent …
Transgenic mice overexpressing the extracellular domain of NCAM are impaired in working memory and cortical plasticity
LH Brennaman, G Kochlamazashvili, L Stoenica… - Neurobiology of …, 2011 - Elsevier
The neural cell adhesion molecule, NCAM, is a pivotal regulator of neural development, with
key roles in axonal and dendritic growth and synaptic plasticity. Alterations in NCAM …
key roles in axonal and dendritic growth and synaptic plasticity. Alterations in NCAM …
The neural cell adhesion molecule promotes FGFR-dependent phosphorylation and membrane targeting of the exocyst complex to induce exocytosis in growth cones
Y Chernyshova, I Leshchyns' ka, SC Hsu… - Journal of …, 2011 - Soc Neuroscience
The exocyst complex is an essential regulator of polarized exocytosis involved in
morphogenesis of neurons. We show that this complex binds to the intracellular domain of …
morphogenesis of neurons. We show that this complex binds to the intracellular domain of …
A human IgM signals axon outgrowth: coupling lipid raft to microtubules
X Xu, AE Warrington, BR Wright… - Journal of …, 2011 - Wiley Online Library
J. Neurochem.(2011) 119, 100–112. Abstract Mouse and human IgMs support neurite
extension from primary cerebellar granule neurons. In this study using primary hippocampal …
extension from primary cerebellar granule neurons. In this study using primary hippocampal …
Enterocytic differentiation is modulated by lipid rafts-dependent assembly of adherens junctions
NT Chartier, MG Lainé, B Ducarouge, C Oddou… - Experimental cell …, 2011 - Elsevier
Integrity of the epithelial barrier is determined by apical junctional complexes which also
participate in the signalling pathways inducing intestinal cell differentiation. Lipid rafts (LR) …
participate in the signalling pathways inducing intestinal cell differentiation. Lipid rafts (LR) …
Neural cell adhesion molecule potentiates the growth of murine melanoma via β-catenin signaling by association with fibroblast growth factor receptor and glycogen …
R Liu, Y Shi, HJ Yang, L Wang, S Zhang, YY Xia… - Journal of Biological …, 2011 - ASBMB
The neural cell adhesion molecule (NCAM) was recently shown to be involved in the
progression of various tumors with diverse effects. We previously demonstrated that NCAM …
progression of various tumors with diverse effects. We previously demonstrated that NCAM …
Neural cell adhesion molecule ablation in mice causes hippocampal dysplasia and loss of septal cholinergic neurons
Y Tereshchenko, F Morellini, A Dityatev… - Journal of …, 2011 - Wiley Online Library
The neural cell adhesion molecule (NCAM) is implicated in nervous system development
and plasticity. In humans, abnormal NCAM expression has been linked to the pathogenesis …
and plasticity. In humans, abnormal NCAM expression has been linked to the pathogenesis …
Immobilized pool of NCAM180 in the postsynaptic membrane is homeostatically replenished by the flux of NCAM180 from extrasynaptic regions
I Leshchyns' ka, MM Tanaka, M Schachner… - Journal of Biological …, 2011 - ASBMB
Homeostatic mechanisms maintaining high levels of adhesion molecules in synapses over
prolonged periods of time remain incompletely understood. We used fluorescence recovery …
prolonged periods of time remain incompletely understood. We used fluorescence recovery …
[HTML][HTML] Direct demonstration of NCAM cis-dimerization and inhibitory effect of palmitoylation using the BRET2 technique
N Kulahin, LG Grunnet, M Lundh, DP Christensen… - FEBS letters, 2011 - Elsevier
Biological activity of the neural cell adhesion molecule (NCAM) depends on both adhesion
and activation of intra-cellular signaling. Based on in vitro experiments with truncated extra …
and activation of intra-cellular signaling. Based on in vitro experiments with truncated extra …
The role of filopodia in the formation of spine synapses
P Arstikaitis - 2011 - open.library.ubc.ca
In the mammalian brain, excitatory (glutamatergic) synapses are mainly located on dendritic
spines; bulbous protrusions enriched with F-actin. Dendritic filopodia are thin protrusions …
spines; bulbous protrusions enriched with F-actin. Dendritic filopodia are thin protrusions …