Extracellular matrix molecules, their receptors, and secreted proteases in synaptic plasticity

J Wlodarczyk, I Mukhina, L Kaczmarek… - Developmental …, 2011 - Wiley Online Library
Neural cells secrete diverse molecules, which accumulate in the extracellular space and
form the extracellular matrix (ECM). Interactions between cells and the ECM are well …

Structural and functional impairments of polysialic acid by a mutated polysialyltransferase found in schizophrenia

R Isomura, K Kitajima, C Sato - Journal of Biological Chemistry, 2011 - ASBMB
Polysialic acid (polySia), a unique acidic glycan modifying neural cell adhesion molecule
(NCAM), is known to regulate embryonic neural development and adult brain functions …

Impaired hippocampal spinogenesis and neurogenesis and altered affective behavior in mice lacking heat shock factor 1

S Uchida, K Hara, A Kobayashi… - Proceedings of the …, 2011 - National Acad Sciences
Aberrant transcriptional regulation in the brain is thought to be one of the key components of
the pathogenesis and pathophysiology of neuropsychiatric disorders. Heat shock factors …

Causal evidence for the involvement of the neural cell adhesion molecule, NCAM, in chronic stress‐induced cognitive impairments

R Bisaz, M Schachner, C Sandi - Hippocampus, 2011 - Wiley Online Library
In rodents, chronic stress induces long‐lasting structural and functional alterations in the
hippocampus, as well as learning and memory impairments. The neural cell adhesion …

Transgenic mice overexpressing the extracellular domain of NCAM are impaired in working memory and cortical plasticity

LH Brennaman, G Kochlamazashvili, L Stoenica… - Neurobiology of …, 2011 - Elsevier
The neural cell adhesion molecule, NCAM, is a pivotal regulator of neural development, with
key roles in axonal and dendritic growth and synaptic plasticity. Alterations in NCAM …

Brain-specific expression of N-acetylglucosaminyltransferase IX (GnT-IX) is regulated by epigenetic histone modifications

Y Kizuka, S Kitazume, M Yoshida… - Journal of Biological …, 2011 - ASBMB
It is well known that biosynthesis of glycans takes place in organ-and tissue-specific
manners and glycan expression is controlled by various factors including …

A novel role for neural cell adhesion molecule in modulating insulin signaling and adipocyte differentiation of mouse mesenchymal stem cells

HJ Yang, YY Xia, L Wang, R Liu, KJ Goh… - Journal of cell …, 2011 - journals.biologists.com
Neural cell adhesion molecule (NCAM) has recently been found on adult stem cells, but its
biological significance remains largely unknown. In this study, we used bone-marrow …

The neural cell adhesion molecule-derived peptide FGL facilitates long-term plasticity in the dentate gyrus in vivo

G Dallérac, M Zerwas, T Novikova, D Callu… - Learning & …, 2011 - learnmem.cshlp.org
The neural cell adhesion molecule (NCAM) is known to play a role in developmental and
structural processes but also in synaptic plasticity and memory of the adult animal. Recently …

Effects of chronic stress and corticosterone on sialidase activity in the rat hippocampus

P Wielgat, A Walesiuk, JJ Braszko - Behavioural brain research, 2011 - Elsevier
Sialidases are acid exoglycosidases that catalyse the removal of sialic acid from non-
reducing end of sialoglucoconjugated substrates. Synaptic plasticity depends on sialylation …

Sensory experience differentially modulates the mRNA expression of the polysialyltransferases ST8SiaII and ST8SiaIV in postnatal mouse visual cortex

MC Belanger, G Di Cristo - PLoS One, 2011 - journals.plos.org
Polysialic acid (PSA) is a unique carbohydrate composed of a linear homopolymer of α-2, 8
linked sialic acid, and is mainly attached to the fifth immunoglobulin-like domain of the …