The loss of control over drug intake that occurs in addiction was initially believed to result
from disruption of subcortical reward circuits. However, imaging studies in addictive …

An ascending sensory pathway that underlies feelings from the body, such as cooling or
toothache, terminates in the posterior insula. Considerable evidence suggests that this …

It is widely believed that people have privileged and authoritative access to their own
thoughts, and many theories have been proposed to explain this supposed fact. The Opacity …

Empathy is thought to play a key role in motivating prosocial behavior, guiding our
preferences and behavioral responses, and providing the affective and motivational base for …

Humans have the ability to control negative affect and perceived fear. Nevertheless, it is still
unclear whether this affect regulation capacity relies on a common neural mechanism in …

As thinking adults depend upon years of practical experience, reasoning about facts and
causes, and language to sustain their knowledge, beliefs and memories, and to understand …

It is becoming increasingly appreciated that affective influences can contribute strongly to
goal-oriented cognition and behavior. However, much work is still needed to properly …

Helplessness is a major concept in depression and a major theme in preclinical and clinical
depression research. For example, in rodents and humans, the learned helplessness (LH) …

In previous research I have theorised that there is a three-step motivational sequence that
drives fertility behaviour, beginning with motivational traits, continuing with fertility desires …

Throughout the centuries, scientific observers have endeavoured to extend their knowledge
of the interrelationships between the brain and its regulatory control of human emotions and …