Cognitive control deficits in schizophrenia: mechanisms and meaning
Although schizophrenia is an illness that has been historically characterized by the
presence of positive symptomatology, decades of research highlight the importance of …
presence of positive symptomatology, decades of research highlight the importance of …
Psychiatric 'diseases' versus behavioral disorders and degree of genetic influence
OJ Bienvenu, DS Davydow, KS Kendler - Psychological medicine, 2011 - cambridge.org
BackgroundPsychiatric conditions in which symptoms arise involuntarily ('diseases') might
be assumed to be more heritable than those in which choices are essential (behavioral …
be assumed to be more heritable than those in which choices are essential (behavioral …
Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4
Nature genetics, 2011 - nature.com
We conducted a combined genome-wide association study (GWAS) of 7,481 individuals
with bipolar disorder (cases) and 9,250 controls as part of the Psychiatric GWAS …
with bipolar disorder (cases) and 9,250 controls as part of the Psychiatric GWAS …
Genetics of schizophrenia: new findings and challenges
PV Gejman, AR Sanders… - Annual review of …, 2011 - annualreviews.org
The work conducted using genome-wide approaches during the past several years has
invigorated the field, and represents the dawn of molecular genetics of schizophrenia. The …
invigorated the field, and represents the dawn of molecular genetics of schizophrenia. The …
Epigenetic studies of psychosis: current findings, methodological approaches, and implications for postmortem research
It has been widely speculated that epigenetic changes may play a role in the etiology of
psychotic illnesses such as schizophrenia and bipolar disorder. Epigenetics is the study of …
psychotic illnesses such as schizophrenia and bipolar disorder. Epigenetics is the study of …
A systematic review and meta‐analysis of the fertility of patients with schizophrenia and their unaffected relatives
H Bundy, D Stahl, JH MacCabe - Acta Psychiatrica …, 2011 - Wiley Online Library
Bundy H, Stahl D, MacCabe JH. A systematic review and meta‐analysis of the fertility of
patients with schizophrenia and their unaffected relatives. Objective: We aimed to …
patients with schizophrenia and their unaffected relatives. Objective: We aimed to …
Developmental history of the subplate zone, subplate neurons and interstitial white matter neurons: relevance for schizophrenia
The subplate zone is a transient cytoarchitectonic compartment of the fetal telencephalic
wall and contains a population of subplate neurons which are the main neurons of the fetal …
wall and contains a population of subplate neurons which are the main neurons of the fetal …
Serotonin 2A receptor antagonists for treatment of schizophrenia
BH Ebdrup, H Rasmussen, J Arnt… - Expert opinion on …, 2011 - Taylor & Francis
Introduction: All approved antipsychotic drugs share an affinity for the dopamine 2 (D2)
receptor; however, these drugs only partially ameliorate the symptoms of schizophrenia. It is …
receptor; however, these drugs only partially ameliorate the symptoms of schizophrenia. It is …
Cell biology of the BLOC-1 complex subunit dysbindin, a schizophrenia susceptibility gene
AP Mullin, A Gokhale, J Larimore, V Faundez - Molecular neurobiology, 2011 - Springer
There is growing interest in the biology of dysbindin and its genetic locus (DTNBP1) due to
genetic variants associated with an increased risk of schizophrenia. Reduced levels of …
genetic variants associated with an increased risk of schizophrenia. Reduced levels of …
Similarities and differences in peripheral blood gene‐expression signatures of individuals with schizophrenia and their first‐degree biological relatives
Several studies have evaluated the potential utility of blood‐based whole‐transcriptome
signatures as a source of biomarkers for schizophrenia. This endeavor has been …
signatures as a source of biomarkers for schizophrenia. This endeavor has been …