Regulation of inflammation in cancer by eicosanoids
Inflammation in the tumor microenvironment is now recognized as one of the hallmarks of
cancer. Endogenously produced lipid autacoids, locally acting small molecule lipid …
cancer. Endogenously produced lipid autacoids, locally acting small molecule lipid …
Phenotypic modulation of macrophages in response to plaque lipids
S Adamson, N Leitinger - Current opinion in lipidology, 2011 - journals.lww.com
Phenotypic modulation of macrophages in response to plaque l... : Current Opinion in
Lipidology Phenotypic modulation of macrophages in response to plaque lipids : Current …
Lipidology Phenotypic modulation of macrophages in response to plaque lipids : Current …
Historical perspective and future directions in platelet research
BS Coller - Journal of Thrombosis and haemostasis, 2011 - Wiley Online Library
Platelets are a remarkable mammalian adaptation that are required for human survival by
virtue of their ability to prevent and arrest bleeding. Ironically, however, in the past century …
virtue of their ability to prevent and arrest bleeding. Ironically, however, in the past century …
Hydrogen sulfide upregulates cyclooxygenase-2 and prostaglandin E metabolite in sepsis-evoked acute lung injury via transient receptor potential vanilloid type 1 …
SF Ang, SWS Sio, SM Moochhala… - The Journal of …, 2011 - journals.aai.org
Hydrogen sulfide (H 2 S) has been shown to promote transient receptor potential vanilloid
type 1 (TRPV1)-mediated neurogenic inflammation in sepsis and its associated multiple …
type 1 (TRPV1)-mediated neurogenic inflammation in sepsis and its associated multiple …
Eicosanoid signalling pathways in the development and progression of colorectal cancer: novel approaches for prevention/intervention
MC Cathcart, J Lysaght, GP Pidgeon - Cancer and Metastasis Reviews, 2011 - Springer
Arachidonic acid metabolism through cyclooxygenase (COX), lipoxygenase (LOX) and
cytochrome P-450 epoxygenase (EPOX) pathways leads to the generation of biologically …
cytochrome P-450 epoxygenase (EPOX) pathways leads to the generation of biologically …
Functional heterogeneity of breast fibroblasts is defined by a prostaglandin secretory phenotype that promotes expansion of cancer-stem like cells
JA Rudnick, LM Arendt, I Klebba, JW Hinds, V Iyer… - PloS one, 2011 - journals.plos.org
Fibroblasts are important in orchestrating various functions necessary for maintaining
normal tissue homeostasis as well as promoting malignant tumor growth. Significant …
normal tissue homeostasis as well as promoting malignant tumor growth. Significant …
The cyclooxygenases
MG Malkowski - Encyclopedia of Inorganic and Bioinorganic …, 2011 - Wiley Online Library
Abstract Cyclooxygenases (COX‐1 and COX‐2) are membrane‐associated, heme‐
containing enzymes that oxygenate arachidonic acid to generate prostaglandin H2 in the …
containing enzymes that oxygenate arachidonic acid to generate prostaglandin H2 in the …
The beneficial role of vitamin D in Alzheimer's disease
KVQ Lu'o'ng, LTH Nguyễn - American Journal of Alzheimer's …, 2011 - journals.sagepub.com
Alzheimer's disease (AD) is the most common form of dementia in the elderly individuals
and is associated with progressive neurodegeneration of the human neocortex. Patients …
and is associated with progressive neurodegeneration of the human neocortex. Patients …
[图书][B] Progress in medicinal chemistry
G Lawton, DR Witty - 2011 - books.google.com
Appropriate selection of biochemical targets is one of the most important drivers of cost
effectiveness in the discovery of new medicines. Despite the many advances in genetics …
effectiveness in the discovery of new medicines. Despite the many advances in genetics …
Focus on inflammation
A Tedgui - Arteriosclerosis, thrombosis, and vascular biology, 2011 - Am Heart Assoc
The term inflammation, from the Latin inflammare (to set on fire), was first used 2000 years
ago by the Roman encyclopedist Aulus Cornelius Celsus, who documented the 4 cardinal …
ago by the Roman encyclopedist Aulus Cornelius Celsus, who documented the 4 cardinal …