Introduction• Perlecan: a pro‐angiogenic proteoglycan• Endorepellin, a C‐terminal fragment
of perlecan with anti‐angiogenic activity• Syndecans in cancer biology• Glypicans and the …

Chitosan has been shown to promote initial wound closure events to prevent blood loss.
Platelet adhesion and activation are crucial early events in these processes after traumatic …

Stroke is the leading cause of long-term disability and the third leading cause of death in the
United States. While most research thus far has focused on acute stroke treatment and …

Endorepellin, the C-terminal module of perlecan, negatively regulates angiogenesis counter
to its proangiogenic parental molecule. Endorepellin (the C-terminal domain V of perlecan) …

Osteocytes project long, slender processes throughout the mineralized matrix of bone,
where they connect and communicate with effector cells. The interconnected cellular …

The development of vascular system depends on the coordinated activity of a number of
distinct families of molecules including growth factors and their receptors, cell adhesion …

Angiogenesis, a neovascularization process induced from the existing parent blood vessels,
is a prerequisite for many physiological and pathological conditions. Under physiological …

Astrogliosis constitutes part of the central nervous system's physiological response to injury.
Considered for decades to be a major challenge for brain repair, recent studies have …

J. Neurochem.(2011) 119, 760–771. Abstract Two of the main stresses faced by cells at the
neurovascular unit (NVU) as an immediate result of cerebral ischemia are oxygen–glucose …

Metastatic prostate tumours are responsible for the majority of deaths associated with
prostate cancer. The most frequent site of prostate cancer metastasis is to bone; over 80% of …