'Autonomic conflict': a different way to die during cold water immersion?

MJ Shattock, MJ Tipton - The Journal of physiology, 2012 - Wiley Online Library
Cold water submersion can induce a high incidence of cardiac arrhythmias in healthy
volunteers. Submersion and the release of breath holding can activate two powerful and …

Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts

Y Shiba, S Fernandes, WZ Zhu, D Filice, V Muskheli… - Nature, 2012 - nature.com
Transplantation studies in mice and rats have shown that human embryonic-stem-cell-
derived cardiomyocytes (hESC-CMs) can improve the function of infarcted hearts,,, but two …

Luteolin limits infarct size and improves cardiac function after myocardium ischemia/reperfusion injury in diabetic rats

D Sun, J Huang, Z Zhang, H Gao, J Li, M Shen, F Cao… - PloS one, 2012 - journals.plos.org
Background The present study was to investigate the effects and mechanism of Luteolin on
myocardial infarct size, cardiac function and cardiomyocyte apoptosis in diabetic rats with …

Mitochondrial permeability transition in the diabetic heart: contributions of thiol redox state and mitochondrial calcium to augmented reperfusion injury

RC Sloan, F Moukdar, CR Frasier, HD Patel… - Journal of molecular and …, 2012 - Elsevier
Mitochondria from diabetic hearts are sensitized to mitochondrial permeability transition
pore (PTP) opening, which may be responsible for the increased propensity for cardiac …

Reduced Cx43 expression triggers increased fibrosis due to enhanced fibroblast activity

JA Jansen, TAB van Veen, S de Jong… - Circulation …, 2012 - Am Heart Assoc
Background—Arrhythmogenic ventricular remodeling is hallmarked by both reduced gap
junction expression and increased collagen deposition. We hypothesized that reduced …

Ischemia reperfusion injury, KATP channels, and exercise-induced cardioprotection against apoptosis

JC Quindry, L Miller, G McGinnis… - Journal of Applied …, 2012 - journals.physiology.org
Exercise is a potent stimulus against cardiac ischemia reperfusion (IR) injury, although the
protective mechanisms are not completely understood. The study purpose was to examine …

[PDF][PDF] Short-term fasting reduces the extent of myocardial infarction and incidence of reperfusion arrhythmias in rats

M Snorek, D Hodyc, V Sedivý, J Durisova… - Physiological …, 2012 - biomed.cas.cz
The effect of three-day fasting on cardiac ischemic tolerance was investigated in adult male
Wistar rats. Anesthetized open-chest animals (pentobarbitone 60 mg/kg, ip) were subjected …

Transport and bioactivity of cyanidin 3-glucoside into the vascular endothelium

L Ziberna, F Tramer, S Moze, U Vrhovsek… - Free radical biology and …, 2012 - Elsevier
Flavonoids are dietary components involved in decreasing oxidative stress in the vascular
endothelium and thus the risk of endothelial dysfunction. However, their very low …

The role of nitric oxide, reactive oxygen species, and protein kinase C in oxytocin-induced cardioprotection in ischemic rat heart

M Faghihi, AM Alizadeh, V Khori, M Latifpour… - Peptides, 2012 - Elsevier
Ischemia–reperfusion injury is a common complication of heart disease that is the leading
cause of death worldwide. Here, we plan to elucidate oxytocin cardioprotection effects …

Cardioprotection of electroacupuncture against myocardial ischemia-reperfusion injury by modulation of cardiac norepinephrine release

W Zhou, Y Ko, P Benharash… - American Journal …, 2012 - journals.physiology.org
Augmentation of cardiac sympathetic tone during myocardial ischemia has been shown to
increase myocardial O2 demand and infarct size as well as induce arrhythmias. We have …