Glimepiride: evidence-based facts, trends, and observations

A Basit, M Riaz, A Fawwad - Vascular health and risk management, 2012 - Taylor & Francis
Type 2 diabetes mellitus is characterized by insulin resistance and progressive β cell failure;
therefore, β cell secretagogues are useful for achieving sufficient glycemic control …

Management of type 2 diabetes mellitus in older adults

KS Kim, SK Kim, KM Sung, YW Cho… - … & metabolism journal, 2012 - synapse.koreamed.org
In the near future, the majority of patients with diabetes will be adults aged 65 or older.
Unlike young adults with diabetes, elderly diabetic people may be affected by a variety of …

Insulin degludec versus insulin glargine in insulin-naive patients with type 2 diabetes: a 1-year, randomized, treat-to-target trial (BEGIN Once Long)

B Zinman, A Philis-Tsimikas, B Cariou… - Diabetes …, 2012 - Am Diabetes Assoc
OBJECTIVE To compare ultra-long-acting insulin degludec with glargine for efficacy and
safety in insulin-naive patients with type 2 diabetes inadequately controlled with oral …

[HTML][HTML] Diabetes: Have We Got It All Wrong?: Insulin hypersecretion and food additives: cause of obesity and diabetes?

BE Corkey - Diabetes care, 2012 - ncbi.nlm.nih.gov
The problemdDiabetes is prevalent and chronic (1). A meta-analysis of studies published
between 1990 and 2006 showed that in adults, obesity prevalence increased from 13 to …

Year in diabetes 2012: the diabetes tsunami

R Sherwin, AM Jastreboff - The Journal of Clinical …, 2012 - academic.oup.com
Diabetes affects more than 300 million individuals globally, contributing to significant
morbidity and mortality worldwide. As the incidence and prevalence of diabetes continue to …

The relationship between glycaemic control and heart failure in 83,021 patients with type 2 diabetes

M Lind, M Olsson, A Rosengren, AM Svensson… - Diabetologia, 2012 - Springer
Aims/hypothesis The aim of this study was to examine the relationship between glycaemic
control and hospitalisation for heart failure in patients with type 2 diabetes. Methods Patients …

Type 2 diabetes from pediatric to geriatric age: analysis of gender and obesity among 120 183 patients from the German/Austrian DPV database

WL Awa, E Fach, D Krakow, R Welp… - European Journal of …, 2012 - academic.oup.com
Aim To characterize the clinical phenotype of type 2 diabetes mellitus (T2DM) with respect to
age, gender, and BMI. Method Anonymized data of 120 183 people with T2DM from the …

Recent advances in incretin‐based therapies

D Russell‐Jones, S Gough - Clinical endocrinology, 2012 - Wiley Online Library
The global burden of type 2 diabetes is growing. Traditional therapies are suboptimal and
there is a clear unmet need for treatments that offer effective glucose control while …

Impact of self-treated hypoglycaemia in type 2 diabetes: a multinational survey in patients and physicians

M Brod, A Rana, AH Barnett - Current medical research and …, 2012 - Taylor & Francis
Objectives: The objectives were to estimate the prevalence of self-treated hypoglycaemia in
patients using basal insulin analogues; identify demographic, treatment related and …

CYP2C metabolism of oral antidiabetic drugs-impact on pharmacokinetics, drug interactions and pharmacogenetic aspects

A Holstein, W Beil, P Kovacs - Expert opinion on drug metabolism …, 2012 - Taylor & Francis
Introduction: The cytochrome P4502C enzymes account for the metabolism of approximately
20% of therapeutic drugs including certain oral antidiabetic drugs (OADs). Areas covered …