[HTML][HTML] HuR function in disease
S Srikantan, M Gorospe - Frontiers in bioscience (Landmark edition …, 2012 - ncbi.nlm.nih.gov
The cytoplasmic events that control mammalian gene expression, primarily mRNA stability
and translation, potently influence the cellular response to internal and external signals. The …
and translation, potently influence the cellular response to internal and external signals. The …
MicroRNA regulation of SIRT1
M Yamakuchi - Frontiers in physiology, 2012 - frontiersin.org
SIRT1 is an NAD-dependent deacetylase that regulates stress response pathways. By
deacetylating transcription factors and co-factors, SIRT1 modulates metabolism …
deacetylating transcription factors and co-factors, SIRT1 modulates metabolism …
Myeloid cell expression of the RNA-binding protein HuR protects mice from pathologic inflammation and colorectal carcinogenesis
A Yiakouvaki, M Dimitriou… - The Journal of …, 2012 - Am Soc Clin Investig
The innate immune response involves a variety of inflammatory reactions that can result in
inflammatory disease and cancer if they are not resolved and instead are allowed to persist …
inflammatory disease and cancer if they are not resolved and instead are allowed to persist …
Regulation of lymphocyte development and function by RNA-binding proteins
Lymphocyte development requires cells to progress through a series of stages, each
associated with changes in gene expression. Intense effort has been invested into …
associated with changes in gene expression. Intense effort has been invested into …
An emerging role of RNA-binding proteins as multifunctional regulators of lymphocyte development and function
Sequence-specific RNA-binding proteins (RBP) and the regulation of RNA decay have long
been recognized as important regulators of the inflammatory response. RBP influence gene …
been recognized as important regulators of the inflammatory response. RBP influence gene …
Decoding the functions of post‐transcriptional regulators in the determination of inflammatory states: focus on macrophage activation
P Kafasla, I Karakasiliotis… - … : Systems Biology and …, 2012 - Wiley Online Library
Inflammation involves a continuum of intercellular interactions and cellular responses
targeting infectious or tissue damage while maintaining homeostasis. At its core, this …
targeting infectious or tissue damage while maintaining homeostasis. At its core, this …
Transcriptome-wide functional analysis of post-transcriptional regulatory interactions of the RNA-binding protein HuR/ELAVL1
S Lebedeva - 2012 - refubium.fu-berlin.de
Post-transcriptional regulation is performed by small RNAs and RNA-binding proteins
(RBPs) which control mRNA splicing, export, degradation and translation efficiency. Each …
(RBPs) which control mRNA splicing, export, degradation and translation efficiency. Each …
HuR and its cleavage are key regulators of apoptotic cell death
C Von Roretz - 2012 - escholarship.mcgill.ca
B. II. Extrinsic activation of caspases 11 B. III. Intrinsic activation of caspases 12 B. III. 1.
Mitochondrial release of cytochrome c 13 B. III. 2. Activation of the apoptosome 14 B. IV. The …
Mitochondrial release of cytochrome c 13 B. III. 2. Activation of the apoptosome 14 B. IV. The …