Renal dysfunction is common in patients with heart failure and is associated with high
morbidity and mortality. Cardiac and renal dysfunction may worsen each other through …

Mineralocorticoid receptor antagonists (MRAs) improve survival and reduce morbidity in
patients with heart failure, reduced ejection fraction (HF–REF), and mild-to-severe …

After publication, dissemination of the message is of paramount importance. Pocket-sized
versions and personal digital assistant (PDA) downloadable versions are useful at the point …

Background Heart failure with preserved ejection fraction is associated with substantial
morbidity and mortality, but effective treatments are lacking. We assessed the efficacy and …

Aims Growth differentiation factor 15 (GDF15), ST2, high‐sensitivity troponin T (hsTnT), and
N‐terminal pro brain natriuretic peptide (NT‐proBNP) are biomarkers of distinct mechanisms …

Context Heart failure with preserved ejection fraction (HFPEF) may be as common and as
lethal as heart failure with reduced ejection fraction (HFREF). Three randomized trials of …

Objectives The objective of this study is to ascertain the effects of the left (LV) and right (RV)
ventricular lead tip position in response to cardiac resynchronization therapy (CRT) …

Aims We explored the effect of treatment with ivabradine, a pure heart rate-slowing agent, on
recurrent hospitalizations for worsening heart failure (HF) in the SHIFT trial. Methods and …

The natriuretic peptide system exerts beneficial cardiorenal effects in chronic heart failure,
whereas activation of the renin–angiotensin–aldosterone system exerts opposing and …

Aims Registries and surveys improve knowledge of the 'real world'. This paper aims to
describe baseline clinical profiles, management strategies, and the in‐hospital outcome of …