White adipose tissue (WAT) is perhaps the most plastic organ in the body, capable of
regeneration following surgical removal and massive expansion or contraction in response …

Upon antigen recognition, naive T cells undergo rapid expansion and activation. The energy
requirements for this expansion are formidable, and T‐cell activation is accompanied by …

Summary Fibroblast growth factor-21 (FGF21) is a circulating hepatokine that beneficially
affects carbohydrate and lipid metabolism. Here, we report that FGF21 is also an inducible …

Adipose tissue is an important site for lipid storage, energy homeostasis, and whole-body
insulin sensitivity. It is important to understand the mechanisms involved in adipose tissue …

Progress has been made in elucidating the cell-surface phenotype of primary adipose
progenitors; however, specific functional markers and distinct molecular signatures of fat …

Adipocyte differentiation is tightly controlled by a transcriptional cascade, which directs the
extensive reprogramming of gene expression required to convert fibroblast-like precursor …

There is growing interest in the potential health threats posed by endocrine-disrupting
chemicals (EDCs) to the reproductive system. Soybean is the most important dietary source …

The utility of human pluripotent stem cells is dependent on efficient differentiation protocols
that convert these cells into relevant adult cell types. Here we report the robust and efficient …

A key issue in the immune system is to generate specific cell types, often with opposing
activities. The mechanisms of differentiation and subtype specification of immune cells such …

Background: In utero exposure of the fetus to a stressor can lead to disease in later life.
Epigenetic mechanisms are likely mediators of later-life expression of early-life events …