From base pair to bedside: molecular simulation and the translation of genomics to personalized medicine

DW Wright, S Wan, N Shublaq… - … Systems Biology and …, 2012 - Wiley Online Library
Despite the promises made that genomic sequencing would transform therapy by
introducing a new era of personalized medicine, relatively few tangible breakthroughs have …

Simulating radiotherapy effect in high‐grade glioma by using diffusive modeling and brain atlases

A Roniotis, K Marias, V Sakkalis… - BioMed Research …, 2012 - Wiley Online Library
Applying diffusive models for simulating the spatiotemporal change of concentration of
tumour cells is a modern application of predictive oncology. Diffusive models are used for …

Computational biomedicine: a challenge for the twenty-first century.

PV Coveney, NW Shublaq - EFMI-STC, 2012 - books.google.com
With the relentless increase of computer power and the widespread availability of digital
patient-specific medical data, we are now entering an era when it is becoming possible to …