Integrated intravital microscopy and mathematical modeling to optimize nanotherapeutics delivery to tumors | AIP Advances | AIP Publishing Skip to Main Content Umbrella Alt Text …
Background The epidermal growth factor receptor (EGFR) signaling pathway and angiogenesis in brain cancer act as an engine for tumor initiation, expansion and response …
SR McDougall, MG Watson, AH Devlin… - Bulletin of mathematical …, 2012 - Springer
Pathological angiogenesis has been extensively explored by the mathematical modelling community over the past few decades, specifically in the contexts of tumour-induced …
We consider a free boundary problem for a system of partial differential equations, which arises in a model of tumor growth with a necrotic core. For any positive number R and 0< ρ< …
Angiogenesis, the formation of new blood vessels, is a crucial step in solid tumour development, as it links the relatively harmless avascular and the potentially fatal vascular …
F Billy, J Clairambault, O Fercoq - Mathematical Methods and Models in …, 2012 - Springer
Cancer is primarily a disease of the physiological control on cell population proliferation. Tissue proliferation relies on the cell division cycle: one cell becomes two after a sequence …
AC Lesart, B van Der Sanden, L Hamard, F Estève… - Microvascular …, 2012 - Elsevier
A computational model is potentially a powerful tool to apprehend complex phenomena like solid tumour growth and to predict the outcome of therapies. To that end, the confrontation of …
A biophysical tool is introduced that seeks to provide a theoretical basis for helping drug design teams assess the most promising drug targets and design optimal treatment …
FG Li, BQ Ai - The European Physical Journal B, 2012 - Springer
Noise induced evolution and transition in an anti-tumor model under immune surveillance are investigated in the presence of additive fractional Gaussian noises. Unlike white …