Overview of Pyridine Nucleotides Review Series

M Nakamura, A Bhatnagar, J Sadoshima - Circulation research, 2012 - Am Heart Assoc
Pyridine nucleotides are abundant soluble coenzymes and they undergo reversible
oxidation and reduction in several biological electron-transfer reactions. They are comprised …

Nuclear factor erythroid 2-related factor 2 signaling in Parkinson disease: a promising multi therapeutic target against oxidative stress, neuroinflammation and cell …

H Kumar, S Koppula, IS Kim… - CNS & Neurological …, 2012 - ingentaconnect.com
Parkinson's disease (PD) is the second most common progressive neurodegenerative
disorder with increased oxidative stress as central component. Till date, treatments related to …

Free radical generation induces epithelial-to-mesenchymal transition in lung epithelium via a TGF-β1-dependent mechanism

MR Gorowiec, LA Borthwick, SM Parker… - Free Radical Biology …, 2012 - Elsevier
Fibrotic remodelling of lung parenchymal and airway compartments is the major contributor
to life-threatening organ dysfunction in chronic lung diseases such as idiopathic pulmonary …

ROS-independent JNK activation and multisite phosphorylation of Bcl-2 link diallyl tetrasulfide-induced mitotic arrest to apoptosis

M Kelkel, C Cerella, F Mack, T Schneider… - …, 2012 - academic.oup.com
Garlic-derived organosulfur compounds including diallyl polysulfides are well known for
various health-beneficial properties and recent reports even point to a potential role of diallyl …

Oxidised fish oil does not influence established markers of oxidative stress in healthy human subjects: a randomised controlled trial

I Ottestad, G Vogt, K Retterstøl, MC Myhrstad… - British Journal of …, 2012 - cambridge.org
Intake of fish oil reduces the risk of CHD and CHD deaths. Marine n-3 fatty acids (FA) are
susceptible to oxidation, but to our knowledge, the health effects of intake of oxidised fish oil …

Using the enzymatic and non-enzymatic antioxidant defense system of the land snail Eobania vermiculata as biomarkers of terrestrial heavy metal pollution

NS El-Shenawy, A Mohammadden… - … and Environmental Safety, 2012 - Elsevier
The present study aimed to investigate the efficacy of antioxidant defense system of the land
snail Eobania vermiculata as biomarkers for terrestrial heavy metal pollution. For this …

N‐acetyl cysteine protects against methamphetamine‐induced dopaminergic neurodegeneration via modulation of redox status and autophagy in dopaminergic cells

P Chandramani Shivalingappa, H Jin… - Parkinson's …, 2012 - Wiley Online Library
Methamphetamine‐(MA‐) induced neurotoxicity is associated with mitochondrial dysfunction
and enhanced oxidative stress. Our previous study demonstrated that MA induces …

Mechanical stress-activated immune response genes via Sirtuin 1 expression in human periodontal ligament cells

SI Lee, KH Park, SJ Kim, YG Kang… - Clinical & …, 2012 - academic.oup.com
Summary Recently, Sirtuin 1 (SIRT1) has been implicated in the molecular control of ageing
and immune response. Although the remodelling of periodontal ligament (PDL) in response …

3′, 4′-Didemethylnobiletin induces phase II detoxification gene expression and modulates PI3K/Akt signaling in PC12 cells

JD Su, JH Yen, S Li, CY Weng, MH Lin, CT Ho… - Free Radical Biology …, 2012 - Elsevier
Oxidative stress is considered a major cause of neurodegenerative disorders. In this work,
we investigated the cytoprotective effects and mechanisms of the citrus flavonoid nobiletin …

Quercetin 3-O-methyl ether protects FL83B cells from copper induced oxidative stress through the PI3K/Akt and MAPK/Erk pathway

HL Tseng, CJ Li, LH Huang, CY Chen, CH Tsai… - Toxicology and applied …, 2012 - Elsevier
Quercetin is a bioflavonoid that exhibits several biological functions in vitro and in vivo.
Quercetin 3-O-methyl ether (Q3) is a natural product reported to have pharmaceutical …