Myocardial ischemia-reperfusion injury is an important cause of impaired heart function in
the early postoperative period subsequent to cardiac surgery. Reactive oxygen species …

Acute myocardial infarction (AMI) with subsequent left ventricular dysfunction and heart
failure continues to be a major cause of morbidity and mortality in the Western world. Rapid …

Rationale: Obstructive sleep apnea (OSA) is a risk factor for cardiovascular death in middle-
aged subjects, but it is not known whether it is also a risk factor in the elderly. Objectives: To …

Coronary heart disease (CHD) is the leading cause of morbidity and mortality worldwide. For
a large number of patients with CHD, coronary artery bypass graft (CABG) surgery remains …

There is extensive evidence that the restoration of blood flow following cerebral ischemia
contributes greatly to the pathophysiology of ischemia mediated brain injury. The initiating …

Background Although recent studies indicate that renal ischemic preconditioning (IPC)
protects the kidney from ischemia-reperfusion (I/R) injury, the precise protective mechanism …

Cardioprotection, ie the reduction in infarct size by pre-, post-, or remote conditioning, has
originally been characterized in young and healthy experimental animals. Over the last two …

In solid organ transplantation, ischemia/reperfusion (IR) injury during organ procurement,
storage and reperfusion is an unavoidable detrimental event for the graft, as it amplifies graft …

A subthreshold ischemic insult applied to an organ such as the heart and/or brain may help
to reduce damage caused by subsequent ischemic episodes. This phenomenon is known …

Cardiovascular inflammation has been regarded as a major cause for heart failure.
However, the mechanisms that are involved in the regulation of cardiovascular inflammation …