Disorders characterized by ischemia/reperfusion (I/R), such as myocardial infarction, stroke,
and peripheral vascular disease, continue to be among the most frequent causes of …

Mast cells are well known for their role in allergic and anaphylactic reactions, as well as their
involvement in acquired and innate immunity. Increasing evidence now implicates mast cells …

Inflammation is a complex and potentially life-threatening condition that involves the
participation of a variety of chemical mediators, signaling pathways, and cell types. The …

Cytokines are small cell signaling protein molecules which encompass a large and diverse
family. They consist of immunomodulating agents such as interleukins and inteferons …

Abstract Objective Studies comparing spondylarthritis (SpA) to rheumatoid arthritis (RA)
synovitis suggest that innate immune cells may play a predominant role in the pathogenesis …

Mast cells are immune cells critical in the pathogenesis of allergic, but also inflammatory and
autoimmune diseases through release of many pro-inflammatory cytokines such as IL-8 and …

Aims and Hypothesis: Mast cells are immune cells known for their role in several
inflammatory and fibrotic diseases. Recent works in mice suggest that mast cells could be …

Abstract Background Autism Spectrum Disorders (ASD) are neurodevelopmental disorders
characterized by varying deficits in social interactions, communication, and learning, as well …

Autism spectrum disorders (ASD) are neurodevelopmental disorders characterized by
varying degrees of dysfunctional communication and social interactions, repetitive and …

Mast cells have been attributed several functions in both health and disease. Mast cell
activation and release of inflammatory mediators are associated with the pathogenesis of …