The delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiology
CJ Guerriero, JL Brodsky - Physiological reviews, 2012 - journals.physiology.org
Protein folding is a complex, error-prone process that often results in an irreparable protein
by-product. These by-products can be recognized by cellular quality control machineries …
by-product. These by-products can be recognized by cellular quality control machineries …
Molecular mechanisms of garlic‐derived allyl sulfides in the inhibition of skin cancer progression
HC Wang, J Pao, SY Lin… - Annals of the New York …, 2012 - Wiley Online Library
Skin cancer is a serious concern whose incidence is increasing at an alarming rate. Allyl
sulfides—ie, sulfur metabolites in garlic oil—have been demonstrated to have anticancer …
sulfides—ie, sulfur metabolites in garlic oil—have been demonstrated to have anticancer …
Role of endoplasmic reticulum stress in age-related susceptibility to lung fibrosis
E Torres-González, M Bueno, A Tanaka… - American journal of …, 2012 - atsjournals.org
The incidence of idiopathic pulmonary fibrosis (IPF) increases with age. The mechanisms
that underlie the age-dependent risk for IPF are unknown. Based on studies that suggest an …
that underlie the age-dependent risk for IPF are unknown. Based on studies that suggest an …
Age and ovariectomy abolish beneficial effects of female sex on rat ventricular myocytes exposed to simulated ischemia and reperfusion
JL Ross, SE Howlett - PLoS One, 2012 - journals.plos.org
Sex differences in responses to myocardial ischemia have been described, but whether
cardiomyocyte function is influenced by sex in the setting of ischemia and reperfusion has …
cardiomyocyte function is influenced by sex in the setting of ischemia and reperfusion has …
[PDF][PDF] Age-Associated Changes in Ca2+-ATPase and Oxidative Damage in Sarcoplasmic Reticulum of Rat Heart.
E Babušíková, J Lehotský, D Dobrota, P Račay… - Physiological …, 2012 - biomed.cas.cz
Age-Associated Changes in Ca2+-ATPase and Oxidative Damage in Sarcoplasmic Reticulum of
Rat Heart Page 1 PHYSIOLOGICAL RESEARCH • ISSN 0862-8408(print) • ISSN …
Rat Heart Page 1 PHYSIOLOGICAL RESEARCH • ISSN 0862-8408(print) • ISSN …
Aging impairs Ca2+ sensitization pathways in gallbladder smooth muscle
B Macias, PJ Gomez-Pinilla, C Camello-Almaraz… - Age, 2012 - Springer
Calcium sensitization is an important physiological process in agonist-induced contraction of
smooth muscle. In brief, calcium sensitization is a pathway that leads to smooth muscle …
smooth muscle. In brief, calcium sensitization is a pathway that leads to smooth muscle …
Age dependent changes in neuronal vulnerability and its metabolic substrates
MS Chitolie - 2012 - etheses.bham.ac.uk
Ageing is an important biological issue affecting all organs in the body. Following from
earlier suggestions that the primary neuronal cultures could be aged\(in\)\(vitro\), the first aim …
earlier suggestions that the primary neuronal cultures could be aged\(in\)\(vitro\), the first aim …
Endoplasmic Reticulum (ER)-stress signalling in the alveolar epithelium
M Hühn - 2012 - jlupub.ub.uni-giessen.de
Endoplasmic Reticulum (ER)-stress, the accumulation of misfolded proteins in the ER, is
assumed to be the cause of several diseases. Recently, enough evidence accumulated to …
assumed to be the cause of several diseases. Recently, enough evidence accumulated to …