A genetic component in the susceptibility to multiple sclerosis (MS) has long been known,
and the first and major genetic risk factor, the HLA region, was identified in the 1970's …

A global interest in therapies for neglected diseases is rising, but traditional biopharma
research and development (R & D) process is prohibitively expensive to justify cost of their …

随着经济的发展, 生活水平的提高, 人们对健康的要求不仅仅限于没有身体的痛苦,
而是逐步扩展到对心理和社会适应的健全状态的追求, 皮肤病学也越来越多地考虑到美学因素 …

The skin, the largest organ in the body, plays a critical role in maintaining internal
homeostasis, serving as a barrier between the external environment and the internal …

Human autoimmune diseases are hallmarked by inappropriate loss-of-tolerance and
selfattacking response of the immune system. Studies included in this thesis are focusing on …

Blond, blauäugig, blass—dass diese Eigenschaften mit einem erhöhten Melanomrisiko
korrelieren, ist schon lange bekannt. Bei der Analyse des Erbguts von mehr als 3000 …

BRAF inhibitors improve melanoma patient survival, but resistance invariably develops.
Here we report the discovery of a novel BRAF mutation that confers resistance to PLX4032 …