Measurement and clinical effect of grey matter pathology in multiple sclerosis

JJG Geurts, M Calabrese, E Fisher… - The Lancet …, 2012 - thelancet.com
During the past 10 years, the intense involvement of the grey matter of the CNS in the
pathology of multiple sclerosis has become evident. On gross inspection, demyelination in …

Segmentation of multiple sclerosis lesions in MR images: a review

D Mortazavi, AZ Kouzani, H Soltanian-Zadeh - Neuroradiology, 2012 - Springer
Introduction Multiple sclerosis (MS) is an inflammatory demyelinating disease that the parts
of the nervous system through the lesions generated in the white matter of the brain. It brings …

Revisiting brain atrophy and its relationship to disability in multiple sclerosis

N Shiee, PL Bazin, KM Zackowski, SK Farrell… - PloS one, 2012 - journals.plos.org
Background Brain atrophy is a well-accepted imaging biomarker of multiple sclerosis (MS)
that partially correlates with both physical disability and cognitive impairment …

Clinical correlates of grey matter pathology in multiple sclerosis

D Horakova, T Kalincik, J Blahova Dusankova… - BMC neurology, 2012 - Springer
Traditionally, multiple sclerosis has been viewed as a disease predominantly affecting white
matter. However, this view has lately been subject to numerous changes, as new evidence …

Reduced head and brain size for age and disproportionately smaller thalami in child-onset MS

A Kerbrat, B Aubert-Broche, V Fonov, S Narayanan… - Neurology, 2012 - AAN Enterprises
Objective: Whole brain and regional volume measurement methods were used to quantify
white matter, gray matter, and deep gray matter structure volumes in a population of patients …

Longitudinal gray matter changes in multiple sclerosis—differential scanner and overall disease‐related effects

K Bendfeldt, L Hofstetter, P Kuster, S Traud… - Human brain …, 2012 - Wiley Online Library
Voxel‐based morphometry (VBM) has been used repeatedly in single‐center studies to
investigate regional gray matter (GM) atrophy in multiple sclerosis (MS). In multi‐center …

Clinical applications of imaging disease burden in multiple sclerosis: MRI and advanced imaging techniques

C Riley, C Azevedo, M Bailey… - Expert review of …, 2012 - Taylor & Francis
This review will address the critical role of radiographic techniques in monitoring multiple
sclerosis disease course and response to therapeutic interventions using conventional …

Neuroimaging in Multiple Sclerosis

G Tedeschi, R Docimo, A Bisecco, A Gallo - … Dysfunction in Multiple …, 2012 - Springer
Abstract Magnetic Resonance Imaging (MRI) is the principal neuroimaging technique
applied to Multiple Sclerosis (MS). Since the early 1990s, conventional MRI (c-MRI) has …

[图书][B] MRI in the Prediction and Diagnosis of Pediatric-Onset Multiple Sclerosis: Insights from Children with Incident CNS Demyelination

LH Verhey - 2012 - search.proquest.com
An acute demyelinating syndrome (ADS) in a child may be a monophasic illness or may
represent the incident attack of multiple sclerosis (MS)–an inflammatory demyelinating …