Genome-wide association studies (GWAS) have evolved over the last ten years into a
powerful tool for investigating the genetic architecture of human disease. In this work, we …

Broadly defined, peripheral vascular disease refers to disease of the extracardiac blood
vessels, including diseases of the arteries, veins, and lymphatics. Peripheral arterial disease …

Objective: Genome-wide association studies (GWAS) require high specificity and large
numbers of subjects to identify genotype–phenotype correlations accurately. The aim of this …

The Strategic Health IT Advanced Research Projects (SHARP) Program, established by the
Office of the National Coordinator for Health Information Technology in 2010 supports …

Objectives Electronic health records (EHR) can allow for the generation of large cohorts of
individuals with given diseases for clinical and genomic research. A rate-limiting step is the …

Objective: There is increasing interest in using electronic health records (EHRs) to identify
subjects for genomic association studies, due in part to the availability of large amounts of …

Objectives: This study sought to compare survival of patients with poorly compressible
arteries (PCA) to those with a normal ankle-brachial index (ABI) and those with peripheral …

Negation of clinical named entities is common in clinical documents and is a crucial factor to
accurately compile patients' clinical conditions and to further support complex phenotype …

Only one low‐density lipoprotein cholesterol (LDL‐C) genome‐wide association study
(GWAS) has been previously reported in‐African Americans. We performed a GWAS of LDL …

This article surveys efforts on text mining of the pharmacogenomics literature, mainly from
the period 2008 to 2011. Pharmacogenomics (or pharmacogenetics) is the field that studies …