Global epidemiology of HIV infection in men who have sex with men

C Beyrer, SD Baral, F Van Griensven, SM Goodreau… - the Lancet, 2012 - thelancet.com
Epidemics of HIV in men who have sex with men (MSM) continue to expand in most
countries. We sought to understand the epidemiological drivers of the global epidemic in …

The evolution of HIV: inferences using phylogenetics

E Castro-Nallar, M Pérez-Losada, GF Burton… - Molecular phylogenetics …, 2012 - Elsevier
Molecular phylogenetics has revolutionized the study of not only evolution but also disparate
fields such as genomics, bioinformatics, epidemiology, ecology, microbiology, molecular …

Simple epidemiological dynamics explain phylogenetic clustering of HIV from patients with recent infection

EM Volz, JS Koopman, MJ Ward… - PLoS computational …, 2012 - journals.plos.org
Phylogenies of highly genetically variable viruses such as HIV-1 are potentially informative
of epidemiological dynamics. Several studies have demonstrated the presence of clusters of …

Phylogenetic insights into regional HIV transmission

AM Dennis, S Hué, CB Hurt, S Napravnik, J Sebastian… - Aids, 2012 - journals.lww.com
Objectives: Despite prevention efforts, new HIV diagnoses continue in the southern United
States, where the epidemic is characterized by significant racial/ethnic disparities. We …

The HIV epidemic: high-income countries

SH Vermund, AJ Leigh-Brown - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
The HIV epidemic in higher-income nations is driven by receptive anal intercourse, injection
drug use through needle/syringe sharing, and, less efficiently, vaginal intercourse. Alcohol …

Transmitted Drug Resistance and Phylogenetic Relationships Among Acute and Early HIV-1–Infected Individuals in New York City

D Castor, A Low, T Evering, S Karmon… - JAIDS Journal of …, 2012 - journals.lww.com
Background: Transmitted drug resistance (TDR) is critical to managing HIV-1–infected
individuals and being a public health concern. We report on TDR prevalence and include …

[PDF][PDF] HIV1 molecular epidemiology in the Balkans: a melting pot for high genetic diversity

M Stanojevic, I Alexiev, D Beshkov, D Gokengin… - AIDS Rev, 2012 - researchgate.net
The Balkans is a gateway between Europe, Asia, and the African continent, a fact with
potential impor‑tant consequences on the epidemiology of HIV‑1 infection in the region. The …

[HTML][HTML] Agent-based and phylogenetic analyses reveal how HIV-1 moves between risk groups: injecting drug users sustain the heterosexual epidemic in Latvia

F Graw, T Leitner, RM Ribeiro - Epidemics, 2012 - Elsevier
Injecting drug users (IDUs) are a driving force for the spread of HIV-1 in Latvia and other
Baltic States, accounting for a majority of cases. However, in recent years, heterosexual …

Episodic HIV risk behavior can greatly amplify HIV prevalence and the fraction of transmissions from acute HIV infection

X Zhang, L Zhong, E Romero-Severson… - … in infectious diseases, 2012 - degruyter.com
A deterministic compartmental model was explored that relaxed the unrealistic assumption
in most HIV transmission models that behaviors of individuals are constant over time. A …

Harnessing evolutionary biology to combat infectious disease

TJ Little, JE Allen, SA Babayan, KR Matthews… - Nature medicine, 2012 - nature.com
Pathogens have remarkable abilities to flout therapeutic intervention. This characteristic is
driven by evolution, either as a direct response to intervention (for example, the evolution of …