Cognitive function, physical activity, and aging: possible biological links and implications for multimodal interventions

E Kraft - Aging, Neuropsychology, and Cognition, 2012 - Taylor & Francis
Increasing evidence shows the positive effect of physical activity (PA) on maintaining
cognitive function. Both processes seem intrinsically linked to each other. The most likely …

Episodic memory function is associated with multiple measures of white matter integrity in cognitive aging

SN Lockhart, ABV Mayda, AE Roach… - Frontiers in human …, 2012 - frontiersin.org
Previous neuroimaging research indicates that white matter injury and integrity, measured
respectively by white matter hyperintensities (WMH) and fractional anisotropy (FA) obtained …

Catechol-o-methyltransferase and Alzheimer's disease: a review of biological and genetic findings

A Serretti, P Olgiati - … (Formerly Current Drug Targets-CNS & …, 2012 - ingentaconnect.com
Alzheimer's disease (AD) is the leading cause of dementia worldwide and is associated with
a marked individual, familial and social burden. Catechol-O-mehyltransferase (COMT) is …

Aging and the neural correlates of source memory: over-recruitment and functional reorganization

J Spaniol, C Grady - Neurobiology of aging, 2012 - Elsevier
Behavioral evidence suggests that memory for context (ie, source memory) is more
vulnerable to age-related decline than item memory. It is not clear, however, whether this …

The effects of aging on material-independent and material-dependent neural correlates of source memory retrieval

MR Dulas, A Duarte - Cerebral Cortex, 2012 - academic.oup.com
Age-related declines in source memory have been observed for various stimuli and
associated details. These impairments may be related to alterations in brain regions …

Failure to modulate attentional control in advanced aging linked to white matter pathology

T Hedden, KRA Van Dijk, EH Shire, RA Sperling… - Cerebral …, 2012 - academic.oup.com
Advanced aging is associated with reduced attentional control and less flexible information
processing. Here, the origins of these cognitive effects were explored using a functional …

Elderly adults through compensatory responses can be just as capable as young adults in inhibiting the flanker influence

S Hsieh, W Fang - Biological Psychology, 2012 - Elsevier
The goals of this study were to determine whether there is an age-related flanker effect,
whether elderly adults produce compensatory responses to overcome their deficiencies, and …

Acute alcohol effects on contextual memory BOLD response: differences based on fragmentary blackout history

RR Wetherill, DM Schnyer… - Alcoholism: Clinical and …, 2012 - Wiley Online Library
Background Contextual memory, or memory for source details, is an important aspect of
episodic memory and has been implicated in alcohol‐induced fragmentary blackouts (FBs) …

Aging and temporal order memory: a comparison of direct and indirect measures

H Blachstein, Y Greenstein, E Vakil - Journal of Clinical and …, 2012 - Taylor & Francis
The purpose of the present study is to compare the effect of aging on direct and indirect
measures of temporal order memory, derived from the Rey Auditory Verbal Learning Test …

Dopaminergic modulation of memory aging: Neurocomputational, neurocognitive, and genetic evidence

SC Li - Memory and Aging, 2012 - api.taylorfrancis.com
Memory and Aging: Current Issues and Future Directions Page 1 305 12 Dopaminergic
modulation of memory aging neurocomputational, neurocognitive, and genetic evidence …