Prion diseases typically have long pre-clinical incubation periods during which time the
infectious prion particle and infectivity steadily propagate in the brain. Abnormal neuritic …

BACKGROUND The Ca2+-dependent protein phosphatase enzyme calcineurin (Cn)(protein
phosphatase 3) is best known for its role as director of the adaptive immune response. One …

Expression of the RCAN1 gene can be induced by multiple stresses. RCAN1 proteins
(RCAN1s) have both protective and harmful effects and are implicated in common human …

RCAN1 is a chromosome 21 gene that controls secretion in endocrine cells, regulates
mitochondrial function, and is sensitive to oxidative stress. Regulator of calcineurin 1 …

Candida albicans is the most common human fungal pathogen. Recent evidence has
revealed the occurrence of apoptosis in C. albicans that is inducible by environmental …

Beef is one of the leading sources of protein, B vitamins, iron, and zinc in human food. Beef
palatability is based on three general criteria: tenderness, juiciness, and flavor, of which …

Glucocorticoid (GC) is a major therapeutic agent for the treatment of leukemia because of its
ability to induce apoptosis in lymphoid cells. The mechanism causing apoptosis, however, is …

The Down syndrome critical region 1 (DSCR1) gene encodes a regulator of the calcineurin
1 (RCAN1) protein, and the elevated levels of RCAN1 are associated with Alzheimer's …

Regulator of calcineurin 1 (RCAN1) is related to the expression of human neurologic
disorders such as Down syndrome, Alzheimer disease, and chromosome 21q deletion …

Uno de los retos más importantes de este siglo en la neurología genómica es construir
mapas de expresión espacial de genes a lo largo de las distintas estructuras cerebrales con …